| Company Name: |
ForeChem (Nantong) Technology Co.,Ltd.
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| Tel: |
513-85982855 18921614129 |
| Email: |
sales@xianxingpharm.com |
| Products Intro: |
Product Name:1-Benzyl 4-(tert-butyl) (S)-2-(cyanomethyl)piperazine-1,4-dicarboxylate
CAS:2158302-00-0
Purity:96% Package:10g,500g,1kg,5kg
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| Company Name: |
ShangHai Angti Biotechnology Co., Ltd.
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| Tel: |
13764913901 |
| Email: |
info@angtibio.com |
| Products Intro: |
Product Name:1-Benzyl 4-(tert-butyl) (S)-2-(cyanomethyl)piperazine-1,4-dicarboxylate
CAS:2158302-00-0
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| Company Name: |
ChengDu TongChuangYuan Pharmaceutical Co.Ltd
|
| Tel: |
028-83379370 13880556291 |
| Email: |
tcy@tcypharm.com |
| Products Intro: |
Product Name:1-Benzyl 4-(tert-butyl) (S)-2-(cyanomethyl)piperazine-1,4-dicarboxylate
CAS:2158302-00-0
Package:1kg ml
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| | 1-Benzyl 4-(tert-butyl) (S)-2-(cyanomethyl)piperazine-1,4-dicarboxylate Basic information |
| | 1-Benzyl 4-(tert-butyl) (S)-2-(cyanomethyl)piperazine-1,4-dicarboxylate Chemical Properties |
| | 1-Benzyl 4-(tert-butyl) (S)-2-(cyanomethyl)piperazine-1,4-dicarboxylate Usage And Synthesis |
| Chemical Properties | White solid | | Synthesis | Dissolve (S)-3-(cyanomethyl)piperazine-1-carboxylic acid tert-butyl ester (2.25g, 10mmol) in 15mL dichloromethane, add N,N-diisopropylethylamine at room temperature (3.87g, 30mmol) was cooled to 0°C, benzyl chloroformate was added dropwise, and reacted at low temperature for 2h. Add 25 mL of water to the reaction solution, extract the aqueous phase with dichloromethane (30 mL×3), combine the organic phases, wash the organic phase with water (20 mL×2), dry with anhydrous sodium sulfate, concentrate, and separate and purify the crude product by silica gel column chromatography (Ethyl acetate/petroleum ether (v/v)=1:20-1:5) to obtain 1-Benzyl 4-(tert-butyl) (S)-2-(cyanomethyl)piperazine-1,4-dicarboxylate (3.1 g, yield: 86%).
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| | 1-Benzyl 4-(tert-butyl) (S)-2-(cyanomethyl)piperazine-1,4-dicarboxylate Preparation Products And Raw materials |
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