| Company Name: |
Anqing YanZhi Pharma Discovery Co.,Ltd. Gold
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| Tel: |
18055651951 |
| Email: |
2272561977@qq.com |
| Products Intro: |
Product Name:BAY-6035
CAS:2247890-13-5
Purity:98%+ Package:5mg; 10mg; 1g; 10g;100g; 1kg; 5Kg; 10Kg
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| | BAY-6035 Basic information |
| Product Name: | BAY-6035 | | Synonyms: | BAY-6035;1H-1,5-Benzodiazepine-7-carboxamide, 1-(3-azabicyclo[3.1.0]hex-3-ylcarbonyl)-N-(2-cyclopropylethyl)-2,3,4,5-tetrahydro-2-methyl-4-oxo-, (2S)-;inhibit,BAY-6035,Histone Methyltransferase,MEKK2,BAY6035,Inhibitor,BAY 6035,SMYD3,methylation;(2S)-1-(3-azabicyclo[3.1.0]hexane-3-carbonyl)-N-(2-cyclopropylethyl)-2-methyl-4-oxo-3,5-dihydro-2H-1,5-benzodiazepine-7-carboxamide;(2S)-1-(3-Azabicyclo[3.1.0]hex-3-ylcarbonyl)-N-(2-cyclopropylethyl)-2,3,4,5-tetrahydro-2-methyl-4-oxo-1H-1,5-benzodiazepine-7-carboxamide;(2S)-1-(3-Azabicyclo[3.1.0]hexane-3-carbonyl)-N-(2-cyclopropylethyl)-2-methyl-4-oxo-2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepine-7-carboxamide | | CAS: | 2247890-13-5 | | MF: | C22H28N4O3 | | MW: | 396.48 | | EINECS: | | | Product Categories: | | | Mol File: | 2247890-13-5.mol |  |
| | BAY-6035 Chemical Properties |
| storage temp. | Store at -20°C | | solubility | DMSO:39.65(Max Conc. mg/mL);100.0(Max Conc. mM)
Ethanol:39.65(Max Conc. mg/mL);100.0(Max Conc. mM) | | form | A crystalline solid |
| | BAY-6035 Usage And Synthesis |
| Description | BAY 6035 is a potent and selective SMYD3 inhibitor. | | in vitro | BAY-6035 specifically inhibited the methylation of MAP3K2 by SMYD3 in a cellular mechanistic assay with an IC50 <100 nM._x000D_
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Reference: SLAS Discov. 2021 Jun 21:24725552211019409. https://journals.sagepub.com/doi/10.1177/24725552211019409?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed | | target | BAY-6035 is a SMYD3 inhibitor. | | storage | Store at -20°C |
| | BAY-6035 Preparation Products And Raw materials |
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