ChemicalBook > Product Catalog >Biochemical Engineering >Amino Acids and Derivatives >Other amino acid derivatives >KYNURENIC ACID

KYNURENIC ACID

KYNURENIC ACID Basic information
Product Name:KYNURENIC ACID
Synonyms:KYNURENIC ACID;4-keto-1H-quinoline-2-carboxylic acid;4-oxo-1H-quinoline-2-carboxylic acid;Kynurenic acid,4-Hydroxyquinoline-2-carboxylic acid;2-Carboxy-4-hydroxyquinoline;4-Hydroxyquinaldinic Acid;AKOS 235-06;4-HYDROXQUINOLINE-2-CARBOXYLIC ACID
CAS:492-27-3
MF:C10H7NO3
MW:189.17
EINECS:207-751-5
Product Categories:Glutamate;Amino Acids & Derivatives;Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Quinolines, Quinazolines and derivatives;Quinoline&Isoquinoline;Hydroxyquinolines;Quinolines;Glutamate receptor;Amino Acids & Derivatives, Aromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals
Mol File:492-27-3.mol
KYNURENIC ACID Structure
KYNURENIC ACID Chemical Properties
Melting point 275 °C (dec.)(lit.)
Boiling point 324.41°C (rough estimate)
density 1.3175 (rough estimate)
refractive index 1.5400 (estimate)
storage temp. Store at RT
form Off-white to tan powder.
pka1.08±0.30(Predicted)
Merck 14,5327
BRN 147451
CAS DataBase Reference492-27-3(CAS DataBase Reference)
EPA Substance Registry System2-Quinolinecarboxylic acid, 4-hydroxy-(492-27-3)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
WGK Germany 3
RTECS UZ9300000
MSDS Information
ProviderLanguage
SigmaAldrich English
ALFA English
KYNURENIC ACID Usage And Synthesis
UsesA product of L-Tryptophan metabolism, possessing neruoactive activity having antiexcitotoxic and anticonvulsant properties.
UsesAn antagonist of NMDA and AMPA/kainate receptors
Biological ActivityBroad spectrum EAA antagonist.
Purification MethodsCrystallise the acid from absolute EtOH. The methyl ester crystallises from MeOH with m 224-226o. [Greenstein & Winitz The Chemistry of the Amino Acids J. Wiley, Vol 3 p2723 1961, Beilstein 22 II 174, 22 III/IV 2245, 22/6 V 280.]
KYNURENIC ACID Preparation Products And Raw materials
Tag:KYNURENIC ACID(492-27-3) Related Product Information
KETAMINE RELATED COMPOUND A (50 MG) (1 -[(2-CHLOROPHENYL)(METHYLIMINO)METHYL]CYLCOPENTA-NOL) Ketamine hydrochloride METHYL 7-CHLORO-4-HYDROXYQUINOLINE-2-CARBOXYLATE METHYL 6-BROMO-4-HYDROXYQUINOLINE-2-CARBOXYLATE METHYL 4-HYDROXY-5,8-DIMETHYLQUINOLINE-2-CARBOXYLATE 5-CHLORO-4-HYDROXYQUINOLINE-2-CARBOXYLIC ACID HCL KYNURENIC ACID ETHYL 4-HYDROXY-8-METHOXYQUINALDATE XANTHURENIC ACID 7-CHLORO-4-HYDROXYQUINOLINE-2-CARBOXYLIC ACID HCL DICHLOROKYNURENIC ACID, 5,7-[3-3H]- 4-METHOXY-2-QUINOLINECARBOXYLIC ACID 5,7-DICHLORO-4-HYDROXY-QUINOLINE-2-CARBOXYLIC ACID ETHYL ESTER 5,7-DICHLOROKYNURENIC ACID SODIUM SALT METHYL 6,8-DIFLUORO-4-HYDROXYQUINOLINE-2-CARBOXYLATE ETHYL 4-HYDROXY-2-QUINOLINECARBOXYLATE KYNURENIC-3,5,6,7,8-D5 ACID xanthurenic acid 8-methyl ether