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L-GLUTAMIC ACID GAMMA-(P-NITROANILIDE) HYDROCHLORIDE

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L-GLUTAMIC ACID GAMMA-(P-NITROANILIDE) HYDROCHLORIDE Suppliers list
Company Name: career henan chemical co
Tel: +86-0371-86658258 15093356674;
Email: factory@coreychem.com
Products Intro: Product Name:L-GLUTAMIC ACID GAMMA-(P-NITROANILIDE) HYDROCHLORIDE
CAS:67953-08-6
Purity:99.0% Package:1g;1USD
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Products Intro: Product Name:GPNA hydrochloride
CAS:67953-08-6
Purity:98.00% Package:1 mL * 10mM (in DMSO)；10 mg；100 mg；25 mg；50 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: GL Biochem(Binhai) Ltd.
Tel: +86-021-61263370 +8615301650015
Email: wuqiuyan@glschina.com
Products Intro: Product Name:H-Glu(PNA)-OH.HCl
Purity:98%; 99% Package:50G,1Kg, 50Kg
Company Name: BOC Sciences
Tel: +16314854226
Email: inquiry@bocsci.com
Products Intro: Product Name:L-Glutamic acid γ-(p-nitroanilide) hydrochloride
CAS:67953-08-6
Purity:>= 99% (HPLC) Remarks:BOC Sciences also provides custom synthesis services for L-Glutamic acid γ-(p-nitroanilide) hydrochloride.
Company Name: Nextpeptide Inc
Tel: +86-0571-81612335 +8613336028439
Email: sales@nextpeptide.com
Products Intro: Product Name:H-Glu(PNA)-OH·HCl
CAS:67953-08-6
Purity:>98% Package:5KG;1KG

L-GLUTAMIC ACID GAMMA-(P-NITROANILIDE) HYDROCHLORIDE manufacturers
L-GLUTAMIC ACID GAMMA-(P-NITROANILIDE) HYDROCHLORIDE Basic information
Product Name:L-GLUTAMIC ACID GAMMA-(P-NITROANILIDE) HYDROCHLORIDE
Synonyms:H-GLU(PNA)-OH HCL;L-GAMMA-GLUTAMYL 4-NITROANILIDE HYDROCHLORIDE;L-GAMMA-GLUTAMYL-P-NITROANILIDE HYDROCHLORIDE;L-GLUTAMIC ACID GAMMA-(P-NITROANILIDE) HYDROCHLORIDE;GAMMA-L-GLUTAMYL-P-NITROANILIDE HYDROCHLORIDE;l-glutamic acid γ-(p-nitroanilide) hydrochloride;L-Glutamic acid g-(p-nitroanilide) hydrochloride;L-y-GLUTAMYL-p-NITROANILIDE HYDROCHLORIDE extrapure
CAS:67953-08-6
MF:C11H14ClN3O5
MW:303.7
EINECS:267-944-5
Product Categories:
Mol File:67953-08-6.mol
L-GLUTAMIC ACID GAMMA-(P-NITROANILIDE) HYDROCHLORIDE Structure
L-GLUTAMIC ACID GAMMA-(P-NITROANILIDE) HYDROCHLORIDE Chemical Properties
storage temp. 2-8°C
solubility Soluble in Water (up to 5 mg/ml).
form solid
color Off-white
Stability:Stable for 1 year from date of purchase as supplied. Solutions in distilled water may be stored at -20° for up to 1 month.
EPA Substance Registry SystemL-Glutamine, N-(4-nitrophenyl)-, monohydrochloride (67953-08-6)
Safety Information
Safety Statements 22-24/25
WGK Germany 3
MSDS Information
ProviderLanguage
SigmaAldrich English
L-GLUTAMIC ACID GAMMA-(P-NITROANILIDE) HYDROCHLORIDE Usage And Synthesis
DescriptionL-γ-Glutamyl-p-nitroanilide (67953-08-6; GPNA) is a substrate for γ-glutamyl transpeptidase. GPNA is used for the determination of γ-glutamyl transpeptidase hydrolytic activity via spectrophotometric monitoring of p-nitroaniline released by the action of the enzyme on GPNA.1 GPNA has also been shown to be an inhibitor of glutamine uptake – solute-linked carrier family A1 member 5 (SLC1A5).2?Cellular uptake of L-glutamine (regulated by SLC1A5) is a rate-limiting step that activates mTOR and is, thus, an interesting cancer chemotherapy target.3
UsesL-Glutamic acid gamma-(p-nitroanilide) is used in methods of treating cancers having a deregulated NRF2/KEAP1 pathway.
References1) Meister?et al. (1981),?γ-Glutamyl transpeptidase; Methods Enzymol.,?77?237 2) Esslinger?et al. (2005),?N-gamma-aryl glutamine analogues as probes of the ASCT2 neutral amino acid transporter binding site; Bioorg. Med. Chem.,?13?1111 3) Nicklin?et al. (2012),?Bidirectional Transport of Amino Acid Regulates mTOR and Autophagy; Cell,?136?521
L-GLUTAMIC ACID GAMMA-(P-NITROANILIDE) HYDROCHLORIDE Preparation Products And Raw materials
Tag:L-GLUTAMIC ACID GAMMA-(P-NITROANILIDE) HYDROCHLORIDE(67953-08-6) Related Product Information
methyl S-(acetamidomethyl)-L-cysteinate monohydrochloride Polyglutamic acid H-L-Glu-OMe·HCl H-GLU(OBZL)-NH2 HCL H-D-MET-D-MET-OH L-Glutamic acid dimethyl ester hydrochloride L-Glutamic acid 5-methyl ester H-Glu(otBu)-Glu(otBu)-OH H-GLU(OTBU)-NH2 HCL L-Glutamic acid 5-tert-butyl 1-methyl ester hydrochloride L-Glutamic acid di-tert-butyl ester hydrochloride L-Glutamic acid 5-tert-butyl ester H-Glu(OMe)-OtBu DL-Phe-pNA phenylalanylglycine H-D-GLU(PNA)-OH N-D-Phenylalanyl-D-tryptophan DL-Ornithine hydrochloride