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ChemeGen
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18818260767 |
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2625930290@qq.com |
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Product Name:Quinapril-d5
CAS:1279029-79-6
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
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| Company Name: |
TargetMol Chemicals Inc.
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4008200310 |
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marketing@tsbiochem.com |
| Products Intro: |
Product Name:Quinapril-d5
CAS:1279029-79-6
Package:5mg/RMB 14700;1mg/RMB 3940
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| Company Name: |
Shanghai isotope chemical co.,ltd
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021-51600108 13062666369 |
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sales@isotopechem.com |
| Products Intro: |
Product Name:Quinapril-d5 HCl
CAS:1279029-79-6
Purity:1mg Package:1mg Remarks:RMCQ80023-1mg
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| Company Name: |
Shanghai Yifei Biotechnology Co. , Ltd.
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021-65675885 18964387627 |
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customer_service@efebio.com |
| Products Intro: |
Product Name:Quinapril-d5
CAS:1279029-79-6
Purity:95% Package:500μg;1mg;5mg
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| | [2H5]-Quinapril Basic information |
| Product Name: | [2H5]-Quinapril | | Synonyms: | [2H5]-Quinapril;Quinapril D5Q: What is
Quinapril D5 Q: What is the CAS Number of
Quinapril D5 Q: What is the storage condition of
Quinapril D5 Q: What are the applications of
Quinapril D5;2-[(2S)-2-[[(1S)-1-(ethoxycarbonyl)-3-phenyl-d5-propyl]amino]-1-oxopropyl]-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid | | CAS: | 1279029-79-6 | | MF: | C25H30N2O5 | | MW: | 438.52 | | EINECS: | | | Product Categories: | | | Mol File: | 1279029-79-6.mol | ![[2H5]-Quinapril Structure](CAS/20211123/GIF/1279029-79-6.gif) |
| | [2H5]-Quinapril Chemical Properties |
| storage temp. | -20°C | | solubility | Methanol: soluble | | form | A solid |
| | [2H5]-Quinapril Usage And Synthesis |
| Uses | Quinapril-d5 is the deuterium labeled Quinapril[1]. | | Biological Activity | Quinapril-d5 is intended for use as an internal standard for the quantification of quinapril by GC- or LC-MS. Quinapril is a prodrug form of the angiotensin converting enzyme (ACE) inhibitor quinaprilat.1,2 In vivo, quinapril (3 mg/kg) reduces mean arterial pressure in renal hypertensive and spontaneously hypertensive rats.2 It inhibits angiotensin I-induced pressor responses in normotensive rats and dogs. Quinapril (10-200 mg/kg) prevents left ventricular heart failure in CHF 14.6 cardiomyopathic hamsters. Formulations containing quinapril have been used in the treatment of hypertension, heart failure, and diabetic nephropathy. | | References | 1.Vago, T., Bevilacqua, M., Conci, F., et al.Angiotensin converting enzyme binding sites in human heart and lung: Comparison with rat tissuesBr. J. Pharmacol.107(3)821-825(1992)
2.Kaplan, H.R., Taylor, D.G., and Olson, S.C.Quinapril: Overview of preclinical dataClin. Cardiol.13(6 Suppl. 7)VII6-VII12(1990) |
| | [2H5]-Quinapril Preparation Products And Raw materials |
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