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2,1,3-Benzoxadiazol-4-amine, N-[2-[4-[(1Z)-1,2-diphenyl-1-buten-1-yl]phenoxy]ethyl]-N-methyl-7-nitro-

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2,1,3-Benzoxadiazol-4-amine, N-[2-[4-[(1Z)-1,2-diphenyl-1-buten-1-yl]phenoxy]ethyl]-N-methyl-7-nitro- Suppliers list
Company Name: TargetMol Chemicals Inc.
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Products Intro: Product Name:FLTX1
CAS:1481401-71-1
Purity:98.42% Package:1mg;53USD|5mg;128USD|10mg;203USD
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Products Intro: Product Name:N-(7-Nitrobenzo[c][1,2,5]oxadiazol-4-yl)demethyltamoxifen
CAS:1481401-71-1
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Products Intro: Product Name:FLTX1
CAS:1481401-71-1
Purity:98% Package:10mg Remarks:V2297
Company Name: TargetMol Chemicals Inc.
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Products Intro: Product Name:FLTX1
CAS:1481401-71-1
Package:10 mg；5 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: Wuhan Topule Biopharmaceutical Co., Ltd
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Products Intro: Product Name:CB38231393
CAS:1481401-71-1
Purity:98% Package:100mg;1g;500g Remarks:Topule Company operates with integrity and has its own laboratory, which supports packaging and customization. Payment will be made after the product has passed third-party testing

2,1,3-Benzoxadiazol-4-amine, N-[2-[4-[(1Z)-1,2-diphenyl-1-buten-1-yl]phenoxy]ethyl]-N-methyl-7-nitro- manufacturers

  • FLTX1
  • FLTX1 pictures
  • $53.00 / 1mg
  • 2025-11-10
  • CAS:1481401-71-1
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  • Purity: 98.46%
  • Supply Ability: 10g
2,1,3-Benzoxadiazol-4-amine, N-[2-[4-[(1Z)-1,2-diphenyl-1-buten-1-yl]phenoxy]ethyl]-N-methyl-7-nitro- Basic information
Product Name:2,1,3-Benzoxadiazol-4-amine, N-[2-[4-[(1Z)-1,2-diphenyl-1-buten-1-yl]phenoxy]ethyl]-N-methyl-7-nitro-
Synonyms:FLTX1;N-(7-Nitrobenzo[c][1,2,5]oxadiazol-4- yl)demethyltamoxife;N-(7-Nitrobenzo[c][1,2,5]oxadiazol-4-yl)demethyltamoxifen;2,1,3-Benzoxadiazol-4-amine, N-[2-[4-[(1Z)-1,2-diphenyl-1-buten-1-yl]phenoxy]ethyl]-N-methyl-7-nitro-;cancer,Estrogen Receptor/ERR,FLTX1,FLTX 1,Inhibitor,fluorescent,Tamoxifen,antiestrogenic,inhibit,non-permeabilized,receptor,breast,FLTX-1,estrogen,permeabilized,uterus;CB38231393;(Z)-N-(2-(4-(1,2-Diphenylbut-1-en-1-yl)phenoxy)ethyl)-N-methyl-7-nitrobenzo[c][1,2,5]oxadiazol-4-amine;FLTX1, 10 mM in DMSO
CAS:1481401-71-1
MF:C31H28N4O4
MW:520.58
EINECS:
Product Categories:
Mol File:1481401-71-1.mol
2,1,3-Benzoxadiazol-4-amine, N-[2-[4-[(1Z)-1,2-diphenyl-1-buten-1-yl]phenoxy]ethyl]-N-methyl-7-nitro- Structure
2,1,3-Benzoxadiazol-4-amine, N-[2-[4-[(1Z)-1,2-diphenyl-1-buten-1-yl]phenoxy]ethyl]-N-methyl-7-nitro- Chemical Properties
Boiling point 679.5±65.0 °C(Predicted)
density 1.258±0.06 g/cm3(Predicted)
solubility DMSO : 25 mg/mL (48.02 mM; Need ultrasonic)
pka-3.81±0.50(Predicted)
form Solid
color Orange to red
Safety Information
MSDS Information
2,1,3-Benzoxadiazol-4-amine, N-[2-[4-[(1Z)-1,2-diphenyl-1-buten-1-yl]phenoxy]ethyl]-N-methyl-7-nitro- Usage And Synthesis
UsesFLTX1 is a fluorescent Tamoxifen derivative that can specifically label intracellular Tamoxifen-binding sites (estrogen receptors) under permeabilized and non-permeabilized conditions. FLTX1 exhibits the potent antiestrogenic properties of Tamoxifen in breast cancer cells. FLTX1 is devoid of the estrogenic agonistic effect on the uterus[1][2].
in vivo

FLTX1 (0.01-1 mg/kg/d; s.c. for 3 d) is lacked of the estrogenic uterotrophic (and also cervical and vaginal), hyperplasic and hypertrophic effects, and failed to alter basal proliferating cell nuclear antigen immunoreactivity in mice and rats[1].

IC 50ERα: 87.5 nM (IC50)
References[1] Marrero-Alonso J, et, al. Unique SERM-like properties of the novel fluorescent tamoxifen derivative FLTX1. Eur J Pharm Biopharm. 2013 Nov;85(3 Pt B):898-910. DOI:10.1016/j.ejpb.2013.04.024
[2] Morales A, et, al. Colocalization of Estrogen Receptors with the Fluorescent Tamoxifen Derivative, FLTX1, Analyzed by Confocal Microscopy. Methods Mol Biol. 2016;1366:163-173. DOI:10.1007/978-1-4939-3127-9_13
2,1,3-Benzoxadiazol-4-amine, N-[2-[4-[(1Z)-1,2-diphenyl-1-buten-1-yl]phenoxy]ethyl]-N-methyl-7-nitro- Preparation Products And Raw materials
Tag:2,1,3-Benzoxadiazol-4-amine, N-[2-[4-[(1Z)-1,2-diphenyl-1-buten-1-yl]phenoxy]ethyl]-N-methyl-7-nitro-(1481401-71-1) Related Product Information
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