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盐酸替诺立定

盐酸替诺立定 更多供应商
公司名称: 深圳菲斯生物科技有限公司  
联系电话: 13380397412
产品介绍: 中文名称:盐酸替诺立定杂质
英文名称:Tenoridine Hydrochloride Impurities
CAS:25913-34-2
纯度:99% HPLC 包装信息:10mg;25mg;50mg;100mg 备注:品牌:sinco,适用于药品研发生产和申报
公司名称: Hangzhou Sage Chemical Co., Ltd.  
联系电话: 0571-86818502
产品介绍: 英文名称:Thieno[2,3-c]pyridine-3-carboxylic acid, 2-aMino-4,5,6,7-tetrahydro-6-(phenylMethyl)-, ethyl ester, Monohydrochloride
CAS:25913-34-2
纯度:98% 包装信息:1g;5g;100g;Bulk
公司名称: TOKYO CHEMICAL INDUSTRY CO., LTD.  
联系电话: 03-3668-0489
产品介绍: 英文名称:Tinoridine Hydrochloride
CAS:25913-34-2
纯度:95-98% 包装信息:25 mg,100 mg
公司名称: 上海陶术生物科技有限公司  
联系电话: 15002134094 021-33632979
产品介绍: 中文名称:盐酸替诺立定
英文名称:Tinoridine hydrochloride
CAS:25913-34-2
纯度:90%-99% 包装信息:1 mL * 10 mM (in DMSO);1 mg;5 mg;25 mg; 备注:试剂级,仅用于科研使用
公司名称: 上海湄水化工科技有限公司  
联系电话: 021-60549325 18616193163
产品介绍: 中文名称:盐酸替诺立定
英文名称:ethyl 2-aMino-6-benzyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate Monohydrochloride
CAS:25913-34-2
纯度:>98% HPLC 包装信息:100g;500g;1kg;10kg
最新发布供应信息
盐酸替诺立定_陕西缔都医药化工有限公司
2021/9/27 8:08:50
盐酸替诺立定
生物活性体外研究体内研究 MSDS 用途与合成方法 盐酸替诺立定价格(试剂级) 上下游产品信息
中文名称:盐酸替诺立定
中文同义词:盐酸替诺立定;2-氨基-6-苄基-4,5,6,7-四氢噻吩并[2,3-C]吡啶-3-甲酸乙酯盐酸盐;盐酸替诺立定杂质
英文名称:ethyl 2-amino-6-benzyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate monohydrochloride
英文同义词:ethyl 2-amino-6-benzyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate monohydrochloride;Nonflamin;Tinoridine Hydrochloride;Tenocyclidine hydrochloride;2-Amino-3-ethoxycarbonyl-6-benzyl-4,5,6,7-tetrahydrothieno(2,3-C)pyridine monohydrochloride;Dimaten;Einecs 247-342-9;Thieno(2,3-C)pyridine-3-carboxylic acid, 2-amino-4,5,6,7-hexahydro-6-(phenylmethyl)-, ethyl ester, monohydrochloride
CAS号:25913-34-2
分子式:C17H21ClN2O2S
分子量:352.87884
EINECS号:247-342-9
相关类别:医药原料;API
Mol文件:25913-34-2.mol
盐酸替诺立定
盐酸替诺立定 性质
熔点 234-235° (dec)
储存条件 Keep in dark place,Inert atmosphere,Room temperature
盐酸替诺立定 用途与合成方法
生物活性Tinoridine hydrochloride (Y-3642)是一种非类固醇的消炎药物,具有有效的抗氧化活性。
体外研究

Tinoridine reduces a stable free radical, diphenyl-p-picrylhydrazyl, in the molar ratio of about 1:2, indicating its free radical scavenging ability. Tinoridine inhibits the lipid peroxidation in rat liver microsomes induced by xanthine-xanthine oxidase system in the presence of ADP and Fe 2+ , in which hydroxyl radical is formed. Tinoridine is demonstrated to be oxidized in the course of the lipid peroxidation by following the fluorescence derived from the oxidation product of tinoridine. It is also oxidized by the xanthine-xanthine oxidase system in the presence of Fe 2+ , but its oxidation is slow in the absence of Fe 2+ and almost completely inhibited by catalase. Tinoridine is also oxidized by H 2 O 2 -Fe 2+ system producing OH (Fenton reaction), but it does not affect the reduction of cytochrome c caused by superoxide radical.

体内研究

CCl 4 aministration produces a marked decrease in the concentrations of liver microsomal cytochrome P-450 and G6Pase, indicating that hepatic endoplasmic reticulum function is disrupted. Prior treatment of the animals with tinoridine (100 mg/kg) significantly reduces the CCl 4 -induced alterations in the enzyme activities, and a rapid recovery toward the normal values is observed.

类别有毒物品
毒性分级中毒
急性毒性口服-大鼠LD50: 1200 毫克/公斤;口服-小鼠LD50:1601 毫克/公斤
可燃性危险特性可燃;燃烧产生有毒氮氧化物, 硫氧化物和氯化氢烟雾
储运特性库房通风低温干燥
灭火剂干粉、泡沫、砂土、二氧化碳, 雾状水
安全信息
毒性LD50 orally in mice: 1601 mg/kg (Nakanishi, 1974)
盐酸替诺立定 价格(试剂级)
更新日期产品编号产品名称CAS编号包装价格
2021/06/02S6472盐酸替诺立定
Tinoridine hydrochloride
25913-34-25mg876.39元
2021/06/02S6472盐酸替诺立定
Tinoridine hydrochloride
25913-34-225mg2375.71元
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