Company Name: |
Xi'an Confluore Biological Technology Co., Ltd.
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Tel: |
+86-156-80926068 +86-15680926068 |
Email: |
1924344760@qq.com |
Products Intro: |
Product Name:Br-PEG3-THP CAS:220568-33-2 Purity:98% HPLC Package:10MG;25MG;50MG;100MG;1G;5G Remarks:For customers outside China,please use the website:www.confluore.com
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Company Name: |
Beijing Jin Ming Biotechnology Co., Ltd.
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Tel: |
010-60605840 15801484223 |
Email: |
psaitong@jm-bio.com |
Products Intro: |
Product Name:Bromo-PEG3-THP CAS:220568-33-2 Package:100mg;250mg;500mg Remarks: 试剂级
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2H-Pyran, 2-[2-[2-(2-bromoethoxy)ethoxy]ethoxy]tetrahydro- manufacturers
- Br-PEG3-THP
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- $0.00 / 1g
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2024-03-25
- CAS:220568-33-2
- Min. Order: 1g
- Purity: >98.00%
- Supply Ability: 1g
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| 2H-Pyran, 2-[2-[2-(2-bromoethoxy)ethoxy]ethoxy]tetrahydro- Basic information |
| 2H-Pyran, 2-[2-[2-(2-bromoethoxy)ethoxy]ethoxy]tetrahydro- Chemical Properties |
Boiling point | 361.7±42.0 °C(Predicted) | density | 1.28±0.1 g/cm3(Predicted) |
| 2H-Pyran, 2-[2-[2-(2-bromoethoxy)ethoxy]ethoxy]tetrahydro- Usage And Synthesis |
Biological Activity | Bromo-PEG3-THP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. | References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
| 2H-Pyran, 2-[2-[2-(2-bromoethoxy)ethoxy]ethoxy]tetrahydro- Preparation Products And Raw materials |
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