| Company Name: |
MedChemexpress LLC
|
| Tel: |
021-58955995 |
| Email: |
sales@medchemexpress.cn |
| Products Intro: |
Product Name:PR66
CAS:2531-04-6
Purity:580RMB/1mg Package:>98%
|
| Company Name: |
MedChemExpress
|
| Tel: |
021-58955995 |
| Email: |
sales@medchemexpress.com |
| Products Intro: |
Product Name:Piperylone
CAS:2531-04-6
|
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| | piperylone Basic information |
| Product Name: | piperylone | | Synonyms: | piperylone;Piperylonum;4-Ethyl-1,2-dihydro-2-(1-methylpiperidin-4-yl)-5-phenyl-3H-pyrazol-3-one;4-ethyl-2-(1-methyl-4-piperidyl)-5-phenyl-1H-pyrazol-3-one;4-ethyl-2-(1-methylpiperidin-4-yl)-5-phenyl-1H-pyrazol-3-one;PR66;3H-Pyrazol-3-one, 4-ethyl-1,2-dihydro-2-(1-methyl-4-piperidinyl)-5-phenyl- | | CAS: | 2531-04-6 | | MF: | C17H23N3O | | MW: | 285.38 | | EINECS: | 2197884 | | Product Categories: | | | Mol File: | 2531-04-6.mol |  |
| | piperylone Chemical Properties |
| Boiling point | 413.0±55.0 °C(Predicted) | | density | 1.121±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | Soluble in DMSO | | pka | pK1 5.90; pK2 9.15(at 25℃) |
| | piperylone Usage And Synthesis |
| Originator | Palerol, Novartis | | Manufacturing Process | A mixture of 8.8 parts of α-ethylbenzoylacetic acid ethyl ester and 5,3 parts of N-methyl-piperidyl-4-hydrazine is allowed to stand for 30 min at 22°C, after which the mixture is heated for 5 hours to 130°C under a pressure of 12 mm. After 4 hours 1-(N-methylpiperidyl-4)-3-phenyl-4-ethylpyrazolone-5 begins crystallize out. The reaction mixture is allowed to cool, after which the crystal mass is triturated with ether and then recrystallized from methanol-ether or from acetone. Melting point 159-161°C. | | Therapeutic Function | Analgesic |
| | piperylone Preparation Products And Raw materials |
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