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| | Thieno[3,2-d]pyrimidine, 6-(4-fluorophenyl)-4-[(1-methyl-1H-tetrazol-5-yl)thio]- Basic information |
| | Thieno[3,2-d]pyrimidine, 6-(4-fluorophenyl)-4-[(1-methyl-1H-tetrazol-5-yl)thio]- Chemical Properties |
| Boiling point | 588.6±60.0 °C(Predicted) | | density | 1?+-.0.1 g/cm3(Predicted) | | pka | 0.24±0.10(Predicted) |
| | Thieno[3,2-d]pyrimidine, 6-(4-fluorophenyl)-4-[(1-methyl-1H-tetrazol-5-yl)thio]- Usage And Synthesis |
| Uses | Protein kinase inhibitor 10 is a protein kinase inhibitor with IC50 values of 28.9, 13.6, and 2.41 μM for TAM receptor, FAK, and KIT, respectively. Protein kinase inhibitor 10 can inhibit abnormal and excessive cell proliferation, showing promise for research in cancer therapy[1]. | | References | [1] Kubbutat et al, Thioether derivatives as protein kinase inhibitors, EP2733146A1, European, 2014-05-21. |
| | Thieno[3,2-d]pyrimidine, 6-(4-fluorophenyl)-4-[(1-methyl-1H-tetrazol-5-yl)thio]- Preparation Products And Raw materials |
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