| Company Name: |
Shanghai meikai technology co., ltd
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| Tel: |
021-68689288 15300790979 |
| Email: |
info@mkbio.com.cn |
| Products Intro: |
Product Name:(2R,3R,4S,5R)-2-(2-chloro-6-((3-methylbut-2-en-1-yl)amino)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol
CAS:65400-39-7
Purity:98% Package:10mg;25mg;100mg
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| | Adenosine, 2-chloro-N-(3-methyl-2-buten-1-yl)- Basic information |
| | Adenosine, 2-chloro-N-(3-methyl-2-buten-1-yl)- Chemical Properties |
| Melting point | 148-150 °C | | Boiling point | 632.9±65.0 °C(Predicted) | | density | 1.65±0.1 g/cm3(Predicted) | | pka | 13.06±0.70(Predicted) |
| | Adenosine, 2-chloro-N-(3-methyl-2-buten-1-yl)- Usage And Synthesis |
| Uses | 2-Chloro-N6-iso-pentenyladenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. | | References | [1] Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500. DOI:10.1016/j.drudis.2021.02.020
[2] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005 |
| | Adenosine, 2-chloro-N-(3-methyl-2-buten-1-yl)- Preparation Products And Raw materials |
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