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| | 5-Chloro-2,4,6-trifluoropyrimidine Basic information |
| Product Name: | 5-Chloro-2,4,6-trifluoropyrimidine | | Synonyms: | 5-CHLORO-2,4,6-TRIFLUOROPYRIMIDINE;AKOS BBS-00006250;5-Chloro-2,4,6-Trifluoropyrimide;2,4,6-TRIFLUORO-5-CHLOROPYRIMIDINE;5-CHLORO-2,4,6-TRIFLUORO-PYRIMIDIN;Pyrimidine, 5-chloro-2,4,6-trifluoro-;5-Chloro-2,4,6-trifluoropyrimidine,97%;5-Chloro-2,4,6-trifluoropyrimidine > | | CAS: | 697-83-6 | | MF: | C4ClF3N2 | | MW: | 168.5 | | EINECS: | 211-807-4 | | Product Categories: | Building Blocks;Halogenated Heterocycles;Heterocyclic Building Blocks;Pyrimidines;Pyrimidine;Building Blocks;C4 to C5;Chemical Synthesis;Fluorinated Building Blocks;Halogenated Heterocycles;Heterocyclic Building Blocks;Heterocyclic Fluorinated Building Blocks;Other Fluorinated Heterocycles;PyrimidinesHeterocyclic Building Blocks | | Mol File: | 697-83-6.mol |  |
| | 5-Chloro-2,4,6-trifluoropyrimidine Chemical Properties |
| Boiling point | 116 °C(lit.) | | density | 1.626 g/mL at 25 °C(lit.) | | refractive index | n20/D 1.439(lit.) | | Fp | >230 °F | | storage temp. | 2-8°C, stored under nitrogen, away from moisture | | pka | -9.30±0.39(Predicted) | | form | Liquid | | color | Clear colorless | | Specific Gravity | 1.626 | | BRN | 610168 | | InChI | 1S/C4ClF3N2/c5-1-2(6)9-4(8)10-3(1)7 | | InChIKey | GOYNRDSJTYLXBU-UHFFFAOYSA-N | | SMILES | Fc1nc(F)c(Cl)c(F)n1 | | CAS DataBase Reference | 697-83-6(CAS DataBase Reference) | | EPA Substance Registry System | Pyrimidine, 5-chloro-2,4,6-trifluoro- (697-83-6) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36-37/39 | | WGK Germany | 3 | | Hazard Note | Irritant | | TSCA | TSCA listed | | HazardClass | IRRITANT, MOISTURE SENSITIVE | | HS Code | 29335990 | | Storage Class | 10 - Combustible liquids | | Hazard Classifications | Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| | 5-Chloro-2,4,6-trifluoropyrimidine Usage And Synthesis |
| Chemical Properties | clear colorless liquid | | Uses | 5-Chloro-2,4,6-trifluoropyrimidine can be used as a starting material to synthesize:
- 4-azido-5-chloro-2,6-difluoro-pyrimidine by azidation reaction with sodium azide.
- 5-chloro triphenoxy pyrimidine by reacting with tetraphenoxysilane in the presence of tetra butyl ammonium fluoride (TBAF).
- 5-chloro-2,6-difluoropyrimidin-4-amine, and 5-chloro-4,6-difluoropyrimidin-2-amine (9:1 ratio) by reacting with ammonia.
- 5-Chloro-N,N -diethyl-2,6-dipyrimidin-4-amine, by treating with diethylamine and DIPEA.
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| | 5-Chloro-2,4,6-trifluoropyrimidine Preparation Products And Raw materials |
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