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J & K SCIENTIFIC LTD.
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18210857532; 18210857532 |
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| Products Intro: |
Product Name:S-(2,4-Dinitrophenyl)-Glutathione
CAS:26289-39-4
Package:100Mg,10Mg
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| | S-(2,4-Dinitrophenyl)-Glutathione Basic information |
| Product Name: | S-(2,4-Dinitrophenyl)-Glutathione | | Synonyms: | 2,4-Dinitrophenyl-S-glutathione;Dinitrophenylglutathione;L-γGlu-S-(2,4-Dinitrophenyl)-L-Cys-Gly-OH;N-[L-γ-Glutamyl-S-(2,4-dinitrophenyl)-L-cysteinyl]glycine;γGlu-S-(2,4-Dinitrophenyl)-L-Cys-Gly-OH;L-γ-Glutamyl-S-(2,4-dinitrophenyl)-L-cysteinylglycine;Glycine, L-γ-glutamyl-S-(2,4-dinitrophenyl)-L-cysteinyl-;(S)-2-amino-5-(((R)-1-((carboxymethyl)amino)-3-((2,4-dinitrophenyl)thio)-1-oxopropan-2-yl)amino)-5-oxopentanoic acid | | CAS: | 26289-39-4 | | MF: | C16H19N5O10S | | MW: | 473.41 | | EINECS: | | | Product Categories: | Glutathione S-Transferase Agents | | Mol File: | 26289-39-4.mol |  |
| | S-(2,4-Dinitrophenyl)-Glutathione Chemical Properties |
| Melting point | 210-212° dec. | | Boiling point | 895.1±65.0 °C(Predicted) | | density | 1.61±0.1 g/cm3(Predicted) | | storage temp. | -20°C Freezer | | solubility | Water: Slightly Soluble | | form | A solid | | pka | 2.21±0.10(Predicted) |
| | S-(2,4-Dinitrophenyl)-Glutathione Usage And Synthesis |
| Description | S-(2,4-Dinitrophenyl)-glutathione is a substrate for glutathione-S-transferase with a kinetic dissociation constant of 7 μM. In vitro, it is transported by multidrug resistance protein 1 (MDR1) and MDR3, which are transporters that confer resistance to some chemotherapeutics. | | Chemical Properties | Light Yellow Solid | | Uses | A substrate for Glutathione-S-Transferase, with a kinetically determined dissociation constant of 7uM. | | Definition | ChEBI: A Glu-Cys-Gly tripeptide glutathione conjugate containing a 2,4-dinitrophenyl substituent on the S of Cys. | | References | [1] V L SCHRAMM. Kinetic studies and active site-binding properties of glutathione S-transferase using spin-labeled glutathione, a product analogue.[J]. The Journal of Biological Chemistry, 1984, 259 2: 714-722.
[2] H ZENG. Transport of amphipathic anions by human multidrug resistance protein 3.[J]. Cancer research, 2000, 60 17: 4779-4784.
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| | S-(2,4-Dinitrophenyl)-Glutathione Preparation Products And Raw materials |
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