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| 5-Aminolevulinic acid hexyl ester hydrochloride Basic information |
| 5-Aminolevulinic acid hexyl ester hydrochloride Chemical Properties |
Melting point | 94° | storage temp. | Inert atmosphere,Room Temperature | solubility | DMSO:41.0(Max Conc. mg/mL);162.86(Max Conc. mM) | form | A solid | color | White to off-white | Water Solubility | H2O: 20mg/mL, clear | Sensitive | Light Sensitive/Hygroscopic | InChI | InChI=1S/C11H21NO3.ClH/c1-2-3-4-5-8-15-11(14)7-6-10(13)9-12;/h2-9,12H2,1H3;1H | InChIKey | LZYXPFZBAZTOCH-UHFFFAOYSA-N | SMILES | C(=O)(OCCCCCC)CCC(=O)CN.Cl |
Hazard Codes | Xi | HS Code | 2922500090 |
| 5-Aminolevulinic acid hexyl ester hydrochloride Usage And Synthesis |
Uses | Diagnostic agent for the diagnosis of bladder cancer. | Uses | 5-Aminolevulinic Acid Hexyl Ester Hydrochloride is used in treating domestic animal cancers through programmed cancer cell death and apoptosis-stimulating proteins. | Biological Activity | Hexaminolevulinate (HAL) hydrochloride is a hexyl ester of 5-Aminolevulinic acid (ALA), a precursor to porphyrins including the photosensitizer protoporphyrin IX (PPIX). Hexaminolevulinate is more lipophilic than ALA, and is 50–100 times more efficient than ALA at inducing PpIX, which accumulates preferentially in neoplastic cells. Hexaminolevulinate administration followed by light activation has been used for fluorescence cystoscopy to enhance detection of bladder cancer, in particular carcinoma in situ (CIS). Hexaminolevulinate is also being studied for use in cancer photodynamic therapy. Hexaminolevulinate followed by irradiation produced DNA oxidative damage and apoptosis. |
| 5-Aminolevulinic acid hexyl ester hydrochloride Preparation Products And Raw materials |
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