| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:cGAS-IN-2
CAS:2765273-11-6
Package:50mg;10mg
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| | Ethanone, 1-[(1S,3R)-6,7-dichloro-1,3,4,5-tetrahydro-1,3-dimethyl-2H-pyrido[4,3-b]indol-2-yl]-2-methoxy- Basic information |
| Product Name: | Ethanone, 1-[(1S,3R)-6,7-dichloro-1,3,4,5-tetrahydro-1,3-dimethyl-2H-pyrido[4,3-b]indol-2-yl]-2-methoxy- | | Synonyms: | Ethanone, 1-[(1S,3R)-6,7-dichloro-1,3,4,5-tetrahydro-1,3-dimethyl-2H-pyrido[4,3-b]indol-2-yl]-2-methoxy-;cGAS-IN-2 | | CAS: | 2765273-11-6 | | MF: | C16H18Cl2N2O2 | | MW: | 341.23 | | EINECS: | | | Product Categories: | | | Mol File: | 2765273-11-6.mol | ![Ethanone, 1-[(1S,3R)-6,7-dichloro-1,3,4,5-tetrahydro-1,3-dimethyl-2H-pyrido[4,3-b]indol-2-yl]-2-methoxy- Structure](CAS/20240320/GIF/2765273-11-6.gif) |
| | Ethanone, 1-[(1S,3R)-6,7-dichloro-1,3,4,5-tetrahydro-1,3-dimethyl-2H-pyrido[4,3-b]indol-2-yl]-2-methoxy- Chemical Properties |
| Boiling point | 523.6±50.0 °C(predicted) | | density | 1.323±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted) | | pka | 14.69±0.60(predicted) | | form | Solid | | color | White to off-white |
| | Ethanone, 1-[(1S,3R)-6,7-dichloro-1,3,4,5-tetrahydro-1,3-dimethyl-2H-pyrido[4,3-b]indol-2-yl]-2-methoxy- Usage And Synthesis |
| Uses | cGAS-IN-2 (compound 109) is a potent inhibitor of Cyclic GMP-AMP Synthase (cGAS), with IC50 of 0.01512 μM for h-cGAS[1]. | | References | [1] Ventus Therapeutics U.S., Inc. Pyrido[4,3-b]indole derivatives and their use as pharmaceuticals. World Intellectual Property Organization, WO2022066851 A1 2022-03-31 |
| | Ethanone, 1-[(1S,3R)-6,7-dichloro-1,3,4,5-tetrahydro-1,3-dimethyl-2H-pyrido[4,3-b]indol-2-yl]-2-methoxy- Preparation Products And Raw materials |
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