- L-Thr-Obzl.HCl
-
- $0.00 / 1kg
-
2024-05-11
- CAS:33645-24-8
- Min. Order: 1kg
- Purity: 98%
- Supply Ability: 1T+
- L-Thr-Obzl.HCl
-
- $1.00 / 1g
-
2020-01-06
- CAS:33645-24-8
- Min. Order: 1g
- Purity: 98%
- Supply Ability: 100KG
|
| | L-Threonine Benzyl Ester Hydrochloride Basic information |
| Product Name: | L-Threonine Benzyl Ester Hydrochloride | | Synonyms: | L-THREONINE BENZYL ESTER HYDROCHLORIDE;L-THREONINE BENZYL ESTER HCL;(2S,3R)-Benzyl 2-aMino-3-hydroxybutanoate hydrochloride;Benzyl L-threoninate hydrochloride;L-Thr-OBzl HCl;L-Threonine Benzyl Ester Hydrochloride;benzyl (2S,3R)-2-amino-3-hydroxybutanoate hydrochloride;L-THREONINE BENZYL ESTER HYDROCHLORIDE USP/EP/BP | | CAS: | 33645-24-8 | | MF: | C11H16ClNO3 | | MW: | 245.70264 | | EINECS: | | | Product Categories: | | | Mol File: | 33645-24-8.mol |  |
| | L-Threonine Benzyl Ester Hydrochloride Chemical Properties |
| Melting point | 128.0 to 132.0 °C | | storage temp. | under inert gas (nitrogen or Argon) at 2-8°C | | form | powder to crystal | | color | White to Almost white | | InChI | InChI=1/C11H15NO3.ClH/c1-8(13)10(12)11(14)15-7-9-5-3-2-4-6-9;/h2-6,8,10,13H,7,12H2,1H3;1H/t8-,10+;/s3 | | InChIKey | IDZGTFSDZJVMSD-YFYURQRANA-N | | SMILES | C(OCC1=CC=CC=C1)(=O)[C@H]([C@H](O)C)N.[H]Cl |&1:10,11,r| | | CAS DataBase Reference | 33645-24-8 |
| | L-Threonine Benzyl Ester Hydrochloride Usage And Synthesis |
| References | [1] Charles M, et al. Serine and Threonine Schiff Base Esters React with β-Anomeric Peracetates in the Presence of BF3·Et2O to Produce β-Glycosides. Journal of Carbohydrate Chemistry, 2010; 29. | | Uses | L-threonine benzyl ester hydrochloride salt was reacted with the diaryl ketimine bis-(4-methoxyphenyl)-methenamine in CH3CN at rt to form the more nucleophilic L-threonine Schiff base (Benzyl N-bis (4-methoxyphenyl)methylene-L-threoninate) in excellent yield. In addition, L-threonine Schiff base, acting as glycosyl acceptor, reacted at rt with simple sugar peracetate donor with BF3·OEt2 promotion to provide the corresponding L-threonine O-linked glycosides in excellent yields and purities[1].
 | | Preparation | The benzyl ester hydrochloride salt, L-Threonine Benzyl Ester Hydrochloride, was prepared from L-threonine and PhCH2OH in the presence of p-toluenesulfonic acid[1]. Specifically, L-Threonine (4.0 g, 34 mmol) and pTsOH acid monohydrate (7.10 g, 38 mmol) were reacted with benzyl alcohol (40 mL) in 50 mL dry benzene using a Dean-Stark apparatus according to the procedure of Petursson and Bald-win. Yield:71.3% |
| | L-Threonine Benzyl Ester Hydrochloride Preparation Products And Raw materials |
|