| Company Name: |
Riedel-de Haen AG
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| Tel: |
800 558-9160 |
| Email: |
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| Products Intro: |
Purity:IgG fraction of antiserum, lyophilized powder Remarks:Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, Ab3
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| Company Name: |
AUSTRAL Biologicals
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| Tel: |
925 543 0018 |
| Email: |
sales@australbiologicals.com |
| Products Intro: |
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| | ANTI-HUMAN SIRTUIN TYPE 5 (SIRT 5) Basic information |
| Product Name: | ANTI-HUMAN SIRTUIN TYPE 5 (SIRT 5) | | Synonyms: | ANTI-HUMAN SIRTUIN TYPE 5 (SIRT 5);Anti-SIRT5 (AB2) antibody produced in rabbit;Anti-NAD-dependent deacetylase sirtuin-5;Anti-SIR2-like protein 5;Anti-SIRT5 antibody produced in rabbit;Anti-SIRT5 (AB1) antibody produced in rabbit;Anti-SIRT5 antibody produced in chicken;Anti-Sirtuin 5 | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![ANTI-HUMAN SIRTUIN TYPE 5 (SIRT 5) Structure]() |
| | ANTI-HUMAN SIRTUIN TYPE 5 (SIRT 5) Chemical Properties |
| storage temp. | -20°C | | form | buffered aqueous glycerol solution |
| | ANTI-HUMAN SIRTUIN TYPE 5 (SIRT 5) Usage And Synthesis |
| Uses | All Prestige Antibodies Powered by Atlas Antibodies are developed and validated by the Human Protein Atlas (HPA) project (www.proteinatlas.org)and as a result, are supported by the most extensive characterization in the industry.
The Human Protein Atlas project can be subdivided into three efforts: Human Tissue Atlas, Cancer Atlas, and Human Cell Atlas. The antibodies that have been generated in support of the Tissue and Cancer Atlas projects have been tested by immunohistochemistry against hundreds of normal and disease tissues and through the recent efforts of the Human Cell Atlas project, many have been characterized by immunofluorescence to map the human proteome not only at the tissue level but now at the subcellular level. These images and the collection of this vast data set can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. To view these protocols and other useful information about Prestige Antibodies and the HPA, visit . | | General Description | SIRT5 (Sirtuin 5) is a mitochondrial matrix protein belonging to the class III of the sirtuin family. It is localized inside the mitochondria and within the cytosol and nucleus. The protein is widely expressed in the brain, heart, liver and kidney. It is composed of very short amino and carboxyl terminal sequences flanking region with the conserved, catalytic sirtuin center domain. | | Biochem/physiol Actions | SIRT5 (Sirtuin 5) is associated with metabolism and aging process. It has been reported in a study that SIRT5 influences urea cycle pathway by NAD-dependent deacetylation and subsequent activation of carbamoyl phosphate synthetase 1 (CPS1), which plays a vital role in the initial step of urea cycle for the detoxification and removal of ammonia. In non-small cell-lung cancer cells, SIRT5 contributions also have been observed for the cancer cell growth and drug resistance. Studies have shown that SIRT5 may possess oncogenic property. |
| | ANTI-HUMAN SIRTUIN TYPE 5 (SIRT 5) Preparation Products And Raw materials |
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