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| | (S)-(-)-3-BENZYLOXY-1,2-PROPANEDIOL Basic information |
| | (S)-(-)-3-BENZYLOXY-1,2-PROPANEDIOL Chemical Properties |
| Melting point | 24-26 °C(lit.) | | alpha | -5.5o (C=20% IN CHLOROFORM) | | Boiling point | 261 °C(lit.) | | density | 1.0966 (rough estimate) | | refractive index | -5.5 ° (C=20, CHCl3) | | Fp | >230 °F | | storage temp. | Sealed in dry,2-8°C | | pka | 13.65±0.20(Predicted) | | form | powder to lump to clear liquid | | color | White or Colorless to Light yellow | | optical activity | [α]20/D 5.5±0.5°, c = 20% in chloroform | | BRN | 2415534 | | CAS DataBase Reference | 17325-85-8(CAS DataBase Reference) |
| Safety Statements | 22-24/25 | | WGK Germany | 3 | | F | 3-10 | | HS Code | 2905399590 |
| | (S)-(-)-3-BENZYLOXY-1,2-PROPANEDIOL Usage And Synthesis |
| Chemical Properties | white to slightly yellow crystalline low melting | | Uses | (S)-(-)-3-Benzyloxy-1,2-propanediol is a useful building block. It is used in the preparation of the nucleotide analog (S)-1-[3-hydroxy-2-(phosphonylmethoxy)propyl]cystosine with antiviral activities. It is also used to synthesize cationic cardiolipin analogs with drug delivery systems such as transfection reagents. | | Purification Methods | Purify the diol by repeated fractional distillation. [Baer et al. J Biol Chem 230 447 1958, Gigg & Gigg J Chem Soc C 1865 1967, Beilstein 6 IV 2247.] |
| | (S)-(-)-3-BENZYLOXY-1,2-PROPANEDIOL Preparation Products And Raw materials |
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