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Curcumin

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Company Name: career henan chemical co
Tel: +86-371-86658258
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Products Intro: Product Name: Curcumin
CAS:458-37-7
Purity:99% Package:1KG;15USD
Company Name: Shaanxi Yikanglong Biotechnology Co., Ltd.
Tel: 17791478691
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Products Intro: Product Name:Curcumin
CAS:458-37-7
Purity:99%(Customizable specifications) Package:1KG;1USD Remarks:Factory stock, quality assurance, price concessions
Company Name: Shenzhen Sendi Biotechnology Co.Ltd.
Tel: 0755-23311925 18102838259
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Products Intro: Product Name:Curcumin
CAS:458-37-7
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Company Name: Henan DaKen Chemical CO.,LTD.
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Products Intro: Product Name:Curcumin
CAS:458-37-7
Purity:99% Package:100g,500g,1KG,10KG,100KG
Company Name: Henan Tianfu Chemical Co.,Ltd.
Tel: 0371-55170693
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Products Intro: CAS:458-37-7
Purity:99% Package:500G;1KG;5KG;25KG

Lastest Price from Curcumin manufacturers

  • Curcumin
  • US $1.00 / KG
  • 2018-10-17
  • CAS:458-37-7
  • Min. Order: 1KG
  • Purity: 99%(Customizable specifications)
  • Supply Ability: 6t
  • Curcumin
  • US $15.00 / KG
  • 2018-07-27
  • CAS:458-37-7
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: 1000KG
  • Curcumin
  • US $100.00 / KG
  • 2018-07-27
  • CAS:458-37-7
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: Customized
Curcumin Basic information
Product Name:Curcumin
Synonyms:Curcuimn;CURCUMIN FROM CURCUMA LONGA CRYSTALL;Curcumin (mixture of curcumin;TURMERIC EXTRACT;1,6-Heptadiene-3,5-dione,1,7-bis(4-hydroxy-3-methoxyphenyl)-,(E,E)-;hydrastis;indianturmeric;kachahaldi
CAS:458-37-7
MF:C21H20O6
MW:368.38
EINECS:207-280-5
Product Categories:Miscellaneous Natural Products;Analytical Chemistry;Antioxidant;Biochemistry;Indicator (pH);pH Indicators;chemical reagent;pharmaceutical intermediate;Chalcone;Miscellaneous;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Diferuloylmethane, Natural Yellow 3, C.I. 75300;pigment;Colorants;Natural Plant Extract;Aromatics;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:458-37-7.mol
Curcumin Structure
Curcumin Chemical Properties
Melting point 183 °C
Boiling point 418.73°C (rough estimate)
density 0.93
vapor density 13 (vs air)
refractive index 1.4155-1.4175
Fp 14℃
storage temp. −20°C
solubility ethanol: 10 mg/mL
form powder
Colour Index 75300
pka8.09(at 25℃)
color orange
PH RangeYellow (7.8) to red-brown (9.2)
Water Solubility Slightly soluble (hot)
λmax430nm
Merck 14,2673
BRN 2306965
Stability:Stable, but may be light sensitive. Incompatible with strong oxidizing agents.
Major ApplicationCosmetics, drug-eluting stents, inhibition of formation of skin-wrinkles, treating alzheimer’s disease, skin diseases, coronary restenosis, diabetes, obesity, leukemia, neurofibromas, cancer, antimicrobial, antiviral, antiinflammatory, antiprostate cancer
CAS DataBase Reference458-37-7(CAS DataBase Reference)
EPA Substance Registry System1,6-Heptadiene-3, 5-dione, 1,7-bis(4-hydroxy-3-methoxyphenyl)-, (1E,6E)-(458-37-7)
Safety Information
Hazard Codes Xi,F
Risk Statements 36/37/38-11
Safety Statements 26-36-16-7-37/39
RIDADR UN1170 - class 3 - PG 2 - Ethanol, solution
WGK Germany 2
RTECS MI5230000
Hazard Note Irritant
TSCA Yes
HazardClass 3
PackingGroup II
HS Code 29145000
Hazardous Substances Data458-37-7(Hazardous Substances Data)
ToxicityLD50 orally in Rabbit: > 5000 mg/kg
MSDS Information
ProviderLanguage
C.I. 75300 English
Curcumin Usage And Synthesis
Chemical Propertiesorange crystalline powder
UsesA natural phenolic compound. Potent anti-tumor agent having anti-inflammatory and anti-oxidant properties. Induces apoptosis in cancer cells and inhibits phorbol ester-induced protein kinase C (PKC) activity. Reported to inhibit production of inflammatory cytokines by peripheral blood monocytes and alveolar macrophages. Potent inhibitor of EGFR tyrosine kinase and IκB kinase. Inhibits inducible nitric oxide synthase (iNOS), cycloxygenase and lipoxygenase. Easily penetrates into the cytoplasm of cells, accumulating in membranous structures such as plasma membrane, endoplasmic reticulum and nuclear envelope.
Usesantiedemic, antiinflammatory, bile stimulant; antibacterial, antifungal, lipo/cyclooxygenase inhibitor
UsesCurcumin is the principal curcuminoid of the popular Indian spice turmeric, which is a member of the ginger family (Zingiberaceae). The curcuminoids are polyphenols and are responsible for the yellow color of turmeric. Curcumin can exist in at least two t
DefinitionChEBI: A beta-diketone that is methane in which two of the hydrogens are substituted by feruloyl groups. A natural dyestuff found in the root of Curcuma longa.
UsesFor preparing curcuma paper, pH range 8-9. In the detection of boron.
General DescriptionOrange-yellow needles.
Air & Water ReactionsSlightly soluble in hot water .
Reactivity ProfileCurcumin is sensitive to light and changes in pH. Curcumin may react with oxidizing materials.
Biological ActivityAntitumor, anti-inflammatory and antioxidant agent. Downregulates expression of reactive-oxygen-generating enzymes (cyclooxygenase, lipoxygenase, iNOS), TNF α , IL-1, IL-6, PKC, EGFR, NF- κ B, I κ B kinase and more. Upregulates expression of PPAR γ , p53, Nrf2. Also displays antimicrobial, antidiabetic neuro- and cardioprotective properties in vivo .
Purification MethodsCrystallise curcumin from EtOH or acetic acid. [Beilstein 8 IV 3697.]
Tag:Curcumin(458-37-7) Related Product Information
CURCUMIN DIACETATE CURCUMIN 3,BISDEMETHOXY CURCUMIN 4-(4-HYDROXY-3-METHOXYPHENYL)-3-BUTEN-2-ONE CURCUMIN, [3H]- (E)-3,4-Dihydroxybenzylideneacetone, 97% 1,6-Octadiene Allylacetone DEMETHOXYCURCUMIN 4-HYDROXY-3-METHOXYCINNAMALDEHYDE TRANS-1-PHENYL-1-PENTENE ISOEUGENOL 1,6-Heptadiene 4-Hydroxybenzylideneacetone 4-Hydroxy-3-methoxystyrene Curcumin Quercetin 4-Methoxyphenylacetone (Trifluoromethoxy)benzene