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Product Name: | NFPS | Synonyms: | NFPS;N-[3-([1,1-Biphenyl]-4-yloxy)-3-(4-fluorophenyl)propyl]-N-methylglycine;2-((3-([1,1'-Biphenyl]-4-yloxy)-3-(4-fluorophenyl)propyl)(methyl)amino)acetic acid;Glycine, N-[3-([1,1'-biphenyl]-4-yloxy)-3-(4-fluorophenyl)propyl]-N-methyl-;2-[[3-(4-fluorophenyl)-3-(4-phenylphenoxy)propyl]-methylamino]acetic acid | CAS: | 405225-21-0 | MF: | C24H24FNO3 | MW: | 393.45 | EINECS: | | Product Categories: | | Mol File: | 405225-21-0.mol | |
storage temp. | Store at +4°C | solubility | Soluble in DMSO > 10 mM | form | Powder |
Uses | NFPS is a non-transportable inhibitor of GlyT1. | Biological Activity | Selective, non-transportable inhibitor of GlyT1 which displays no activity on GlyT2 or the transport of proline, GABA or glutamate (IC 50 values are 2.8, 9.8 and? 56000 nM for hGlyT1, rGlyT1 and rGlyT2 respectively). Enhances the amplitude of the NMDA component of glutamatergic EPSCs. | storage | Store at +4°C |
| NFPS Preparation Products And Raw materials |
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