- Veliparib dihydrochloride
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- $0.00/ kg
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2023-12-26
- CAS:912445-05-7
- Min. Order: 1kg
- Purity: 99%, Single impurity＜0.1
- Supply Ability: 1 ton
- ABT-888
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- $1.00 / 10g
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2022-12-29
- CAS:912445-05-7
- Min. Order: 10g
- Purity: 99.5%
- Supply Ability: 1000kg
- ABT-888
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- $1.00 / 1KG
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2019-07-06
- CAS:912445-05-7
- Min. Order: 1KG
- Purity: 98%
- Supply Ability: 100KG
Related articles - Biological activity ABT-888
- Veliparib (ABT-888) is a potent inhibitor of PARP1 and PARP2 with Ki of 5.2 nM and 2.9 nM in cell-free assays.
- Oct 11，2019
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| | ABT-888 Basic information |
| Product Name: | ABT-888 | | Synonyms: | ABT-888;2-[(2R)-2-Methylpyrrolidin-2-yl]-1H-benimidazole-4-
carboxamide,dihydrochloridesalt;2-[(2R)-2-Methyl-2-pyrrolidinyl]-1H-benzimidazole-4-carboxamide dihydrochloride;Veliparib dihydrochloride;ABT-888(Veliparib dihydrochloride);ABT-888 dihydrochloride;ABT888 HCl;Veliparib hydrochloride | | CAS: | 912445-05-7 | | MF: | C13H16N4O | | MW: | 244.296 | | EINECS: | 1592732-453-0 | | Product Categories: | Inhibitors;Inhibitor;API | | Mol File: | 912445-05-7.mol |  |
| | ABT-888 Chemical Properties |
| Melting point | >173°C (dec.) | | storage temp. | Refrigerator | | solubility | Methanol (Slightly, Heated), THF (Slightly, Heated) | | form | Colorless to white crystalline solid. | | color | Off-White to Dark Yellow |
| | ABT-888 Usage And Synthesis |
| Uses | ABT-888 is a potent, orally bioavailable PARP-1/-2 inhibitor shown to potentiate DNA damaging agents. The ability to potentiate temozolomide (TMZ) and develop a biological marker for PARP inhibition was evaluated in vivo. Potent PARP inhibitor. | | storage | Store at -20°C |
| | ABT-888 Preparation Products And Raw materials |
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