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6-oxo-6,7,8,9,10,11-hexahydrocyclohepta[c][1]benzopyran-3-yl sulfaMate

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6-oxo-6,7,8,9,10,11-hexahydrocyclohepta[c][1]benzopyran-3-yl sulfaMate Suppliers list
Company Name: ATK CHEMICAL COMPANY LIMITED
Tel: +undefined-21-51877795
Email: ivan@atkchemical.com
Products Intro: Product Name:STX64
CAS:288628-05-7
Purity:0.99 Package:5MG;10MG;50MG;100MG,1G,5G
Company Name: Career Henan Chemica Co
Tel: +86-0371-86658258 15093356674;
Email: laboratory@coreychem.com
Products Intro: Product Name:(6-oxo-8,9,10,11-tetrahydro-7H-cyclohepta[c]chromen-3-yl) sulfamate
CAS:288628-05-7
Purity:97%99% crystal Package:1KG;0.01USD
Company Name: Labnetwork lnc.
Tel: +86-27-50766799 +8618062016861
Email: contact@labnetwork.com
Products Intro: Product Name:6-oxo-6,7,8,9,10,11-hexahydrocyclohepta[c]chromen-3-yl sulfamate
CAS:288628-05-7
Purity:95% Package:100g; 1kg Remarks:LN01346276
Company Name: InvivoChem
Tel: +1-708-310-1919 +1-13798911105
Email: sales@invivochem.cn
Products Intro: Product Name:Irosustat
CAS:288628-05-7
Purity:98% Package:1mg Remarks:V4046
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354
Email: support@targetmol.com
Products Intro: Product Name:Irosustat；STX64;BN83495;667-Coumate
CAS:288628-05-7
Package:1 mL * 10mM (in DMSO)；10 mg；2 mg；25 mg；5 mg；50 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
6-oxo-6,7,8,9,10,11-hexahydrocyclohepta[c][1]benzopyran-3-yl sulfaMate Basic information
Product Name:6-oxo-6,7,8,9,10,11-hexahydrocyclohepta[c][1]benzopyran-3-yl sulfaMate
Synonyms:6-oxo-6,7,8,9,10,11-hexahydrocyclohepta[c][1]benzopyran-3-yl sulfaMate;BN 83495;Irosustat;STX 64;6-oxo-6,7,8,9,10,11-hexahydrocyclohepta[c]chromen-3-yl sulfamate;DSLPMJSGSBLWRE-UHFFFAOYSA-N;STX64 - BN83495 | Irosustat | 667 Coumate;COUMATE. Irosustat.
CAS:288628-05-7
MF:C14H15NO5S
MW:309.34
EINECS:604-604-1
Product Categories:
Mol File:288628-05-7.mol
6-oxo-6,7,8,9,10,11-hexahydrocyclohepta[c][1]benzopyran-3-yl sulfaMate Structure
6-oxo-6,7,8,9,10,11-hexahydrocyclohepta[c][1]benzopyran-3-yl sulfaMate Chemical Properties
Melting point 170.1-173.4 °C
Boiling point 544.1±60.0 °C(Predicted)
density 1.48±0.1 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMSO: >20mg/mL
form white powder
pka8.26±0.70(Predicted)
Safety Information
WGK Germany 3
MSDS Information
6-oxo-6,7,8,9,10,11-hexahydrocyclohepta[c][1]benzopyran-3-yl sulfaMate Usage And Synthesis
UsesSTX64 is a potent, irreversible inhibitor of steroid sulfatase.
Biochem/physiol ActionsSTX64 is a potent, irreversible inhibitor of steroid sulfatase. Inhibition of steroid sulfatase (STS), the enzyme responsible for the hydrolysis of steroid sulfates, represents a potential novel treatment for postmenopausal women with hormone-dependent breast cancer. Estrone and DHEA are formed by this sulfatase pathway and can be converted to steroids (estradiol and androstenediol, respectively), which have potent estrogenic properties. STX64 (667 coumate) is a potent tricylic coumarin-based sulfamate that irreversibly inhibits STS activity (IC50 = 8 nM in a placental microsomal assay system). Estrone sulfamate (EMATE) is also a potent STS inhibitor, but has estrogenic activity.
storageStore at -20°C
6-oxo-6,7,8,9,10,11-hexahydrocyclohepta[c][1]benzopyran-3-yl sulfaMate Preparation Products And Raw materials
Tag:6-oxo-6,7,8,9,10,11-hexahydrocyclohepta[c][1]benzopyran-3-yl sulfaMate(288628-05-7) Related Product Information