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| | 4-Guanidinobutyl 4-hydroxy-3,5-diMethoxybenzoate hydrochloride Basic information |
| Product Name: | 4-Guanidinobutyl 4-hydroxy-3,5-diMethoxybenzoate hydrochloride | | Synonyms: | 4-Hydroxy-3,5-dimethoxybenzoic acid 4-[(aminoiminomethyl)amino]butyl ester monohydrochloride;Leonurin monohydrochloride;4-Guanidinobutyl 4-hydroxy-3,5-diMethoxybenzoate hydrochloride;SCM-198 hydrochloride;SCM-198 HCl;Leonurine hydrochloride-RM;Leonurine Hydrochloride(P);Leonurine hydrochloride, 10 mM in DMSO | | CAS: | 24735-18-0 | | MF: | C14H22ClN3O5 | | MW: | 347.79458 | | EINECS: | | | Product Categories: | | | Mol File: | 24735-18-0.mol |  |
| | 4-Guanidinobutyl 4-hydroxy-3,5-diMethoxybenzoate hydrochloride Chemical Properties |
| Melting point | 194℃ | | storage temp. | Sealed in dry,Room Temperature | | solubility | DMSO (Slightly), Methanol (Very Slightly, Heated) | | form | Solid | | color | White to Off-White |
| | 4-Guanidinobutyl 4-hydroxy-3,5-diMethoxybenzoate hydrochloride Usage And Synthesis |
| Chemical Properties | White crystalline powder, easily soluble in methanol and water, derived from Leonurus artemisia (Laur.) SY Hu F. | | Uses | Leonurine Hydrochloride is an alkaloid plant extract used in the treatment of uterine disorders. Used in the modification of uterine contractions in rats. | | in vivo | Leonurine (10 mg/kg/d, p.o.) significantly increases the expressions of PPARγ, LXRα, ABCA1 and ABCG1, and decreases both TG and TC levels in serum of mice[1]. Leonurine hydrochloride (50, 100, 200 mg/kg) improves intracellular lipid accumulation via activating AMPK/SREBP1 pathway, enhances biochemical parameters, reduces hepatic lipoperoxide and increases antioxidant levels in mice[2]. Leonurine (20 mg/kg, p.o.) ameliorates osteoarthritis development in mouse DMM model[3]. |
| | 4-Guanidinobutyl 4-hydroxy-3,5-diMethoxybenzoate hydrochloride Preparation Products And Raw materials |
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