| Company Name: |
Nanchang Zhenshi Biotechnology Co., Ltd Gold
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| Tel: |
18679828511 |
| Email: |
408289529@qq.com |
| Products Intro: |
Product Name:PC 190723
CAS:951120-33-5
Purity:98% Package:10mg;25mg;100mg;250mg;500mg;1g;5g
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| Company Name: |
J & K SCIENTIFIC LTD.
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| Tel: |
18210857532; 18210857532 |
| Email: |
jkinfo@jkchemical.com |
| Products Intro: |
Product Name:3-[(6-Chlorothiazolo[5,4-b]pyridin-2-yl)Methoxy]-2,6-difluorobenzaMide
CAS:951120-33-5
Package:50Mg,5Mg
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| Company Name: |
Beijing Yisiyan Technology Research Center
|
| Tel: |
010-56645598 13366904824 |
| Email: |
bjkaida@163.com |
| Products Intro: |
Product Name:PC 190723
CAS:951120-33-5
Purity:97% Package:10mg/;25mg/;50mg/;100mg/;500mg/;1000mg/
|
| Company Name: |
Shanghai TaoSu Biochemical Technology Co., Ltd.
|
| Tel: |
021-33632979 |
| Email: |
info@tsbiochem.com |
| Products Intro: |
Product Name:3-[(6-Chlorothiazolo[5,4-b]pyridin-2-yl)Methoxy]-2,6-difluorobenzaMide
CAS:951120-33-5
Purity:90% Package:5Mg;50Mg;;
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- PC190723
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- $228.00 / 1mg
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2025-11-10
- CAS:951120-33-5
- Min. Order:
- Purity: 97.64%
- Supply Ability: 10g
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| | PC 190723 Basic information |
| Product Name: | PC 190723 | | Synonyms: | 3-((6-chlorothiazolo[5,4-b]pyridin-2-yl)Methoxy)-2,6-difluorobenzaMide;3-[(6-chloro-[1,3]thiazolo[5,4-b]pyridin-2-yl)methoxy]-2,6-difluorobenzamide;PC190723;Benzamide, 3-[(6-chlorothiazolo[5,4-b]pyridin-2-yl)methoxy]-2,6-difluoro- | | CAS: | 951120-33-5 | | MF: | C14H8ClF2N3O2S | | MW: | 355.75 | | EINECS: | | | Product Categories: | Amines, Aromatics, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds | | Mol File: | 951120-33-5.mol |  |
| | PC 190723 Chemical Properties |
| Melting point | 218 °C | | Boiling point | 462.3±45.0 °C(Predicted) | | density | 1.593±0.06 g/cm3(Predicted) | | pka | 14.15±0.50(Predicted) | | form | Solid | | color | Light yellow to yellow | | InChI | InChI=1S/C14H8ClF2N3O2S/c15-6-3-8-14(19-4-6)23-10(20-8)5-22-9-2-1-7(16)11(12(9)17)13(18)21/h1-4H,5H2,(H2,18,21) | | InChIKey | INYJNSBDHOVLAH-UHFFFAOYSA-N | | SMILES | C(N)(=O)C1=C(F)C=CC(OCC2=NC3=CC(Cl)=CN=C3S2)=C1F |
| | PC 190723 Usage And Synthesis |
| Uses | 3-[(6-Chlorothiazolo[5,4-b]pyridin-2-yl)methoxy]-2,6-difluorobenzamide is a small molecule cell-cycle inhibitor and has been used as an antibacterial agent. 3-[(6-Chlorothiazolo[5,4-b]pyridin-2-yl)methoxy]-2,6-difluorobenzamide was found to inhibit bacterial cell division protein FtsZ. | | in vivo | PC190723 (30 mg/kg; subcutaneous/intravenous injection; single dose) has antibacterial effect in a mouse model of S. aureusinfection[1]. | Animal Model: | S. aureus treated mice[1] | | Dosage: | 30 mg/kg | | Administration: | Subcutaneous/intravenous injection; Single dose | | Result: | Resulted in a 100% survival of mice inoculated intraperitoneally with a potentially lethal dose of S. aureus, as compared with a 0% survival for the group receiving no compound.
Produced dose-dependent efficacy for both routes of administration with ED50 were 7.3 and 10.2 mg/kg for S.C. and I.V. administration, respectively.
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| | PC 190723 Preparation Products And Raw materials |
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