| Company Name: |
ChemStrong Scientific Co.,Ltd
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0755-0755-66853366 13670046396 |
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sales@chem-strong.com |
| Products Intro: |
Product Name:GerMicidin A
CAS:150973-78-7
Purity:95% HPLC Package:10mg;25mg;50mg;100mg
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| Company Name: |
Lynnchem
|
| Tel: |
86-(0)29-85992781 17792393971 |
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info@lynnchem.com |
| Products Intro: |
Product Name:GerMicidin A
CAS:150973-78-7
Purity:>95% by HPLC Package:1mg;5mg
|
| Company Name: |
Novachemistry
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| Tel: |
44-20819178-90 02081917890 |
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info@novachemistry.com |
| Products Intro: |
Product Name:Germicidin B
CAS:150973-78-7
Purity:>95% by HPLC Package:1mg;5mg
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| | GerMicidin A Basic information |
| | GerMicidin A Chemical Properties |
| Boiling point | 283.6±40.0 °C(Predicted) | | density | 1.130±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | Soluble in DMSO | | form | solid | | pka | 5.36±0.50(Predicted) |
| | GerMicidin A Usage And Synthesis |
| Description | Germicidin A is a pyranone originally derived from S. viridochromogenes that acts as a reversible, autoregulative inhibitor of spore germination and hyphal elongation in the genus Streptomyces at concentrations as low as 200 pM. During germination, spores of Streptomyces excrete germicidin A along with other germicidin homologs, which inhibit germination of its own arthrospores. At higher concentrations, germicidin A can inhibit the porcine Na+/K+-activated ATPase (ID50 = 100 μM) and prevent the germination of the cress L. sativum. | | Uses | Germicidin A is an extremely potent autoregulator. | | Uses | Germicidin A is a pyranone isolated from Streptomyces sp. in 1993. Germicidin A is an extremely potent autoregulator of the sporulation of the producing strain, and spores of closely related species. Inhibition is detected at 0.1 ng/ml and is orders of magnitude more potent than a diverse range of antibiotics. | | references | [1] petersen f, zhner h, metzger j w, et al. germicidin, an autoregulative germination inhibitor of streptomyces viridochromogenes nrrl b-1551[j]. the journal of antibiotics, 1993, 46(7): 1126-1138.
[2] aoki y, matsumoto d, kawaide h, et al. physiological role of germicidins in spore germination and hyphal elongation in streptomyces coelicolor a3 (2)[j]. the journal of antibiotics, 2011, 64(9): 607-611. |
| | GerMicidin A Preparation Products And Raw materials |
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