| Company Name: |
Creative Enzymes |
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1-516-855-7709 |
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info@creative-enzymes.com |
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| | N-(2'-(R)-hydroxyarachidoyl)-D-erythro-sphingosine Basic information |
| Product Name: | N-(2'-(R)-hydroxyarachidoyl)-D-erythro-sphingosine | | Synonyms: | N-(2'-(R)-hydroxyarachidoyl)-D-erythro-sphingosine;20:0(2R-OH) Ceramide;N-(2'-(R)-HYDROXYARACHIDOYL)-D-ERYTHRO-SPHINGOSINE;20:0(2R-OH) CERAMIDE;Eicosanamide, 2-hydroxy-N-[(1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]-, (2R)- | | CAS: | 943147-54-4 | | MF: | C38H75NO4 | | MW: | 610.01 | | EINECS: | | | Product Categories: | | | Mol File: | 943147-54-4.mol |  |
| | N-(2'-(R)-hydroxyarachidoyl)-D-erythro-sphingosine Chemical Properties |
| storage temp. | -20°C | | form | powder | | InChIKey | CFYLSUZUMMPFNC-PLHXSOCRSA-N | | SMILES | CCCCCCCCCCCCC/C=C/[C@@H](O)[C@@H](NC([C@H](O)CCCCCCCCCCCCCCCCCC)=O)CO |
| WGK Germany | WGK 3 | | Storage Class | 11 - Combustible Solids |
| | N-(2'-(R)-hydroxyarachidoyl)-D-erythro-sphingosine Usage And Synthesis |
| Uses | Ceramides containing 2-hydroxy fatty acids (hFA) group are mainly found in the epidermis. 20:0(2R-OH) Ceramide is a 2R hydroxylated arachidic acid-containing ceramide. | | Biological Activity | Hydroxy fatty acid (hFA)-sphingolipids play a vital role in cell signaling. hFA-ceramides contribute to the permeability barrier function of the surface epithelium of the skin. Fatty acid 2-hydroxylase (FA2H) catalyzes the synthesis of hFA-ceramides. Impaired function of FA2H causes nervous system disorders leukodystrophy and spastic paraparesis in humans. hFA-ceramides are essential for PM02734, an antitumor drug to exhibit its activity. |
| | N-(2'-(R)-hydroxyarachidoyl)-D-erythro-sphingosine Preparation Products And Raw materials |
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