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| | 4-Trifluoromethoxyphenylboronic acid Basic information |
| | 4-Trifluoromethoxyphenylboronic acid Chemical Properties |
| Melting point | 123-127 °C(lit.) | | Boiling point | 256.6±50.0 °C(Predicted) | | density | 1.41±0.1 g/cm3(Predicted) | | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | | solubility | soluble in Methanol | | pka | 8.29±0.10(Predicted) | | form | Crystalline Powder | | color | White to beige | | BRN | 8548201 | | InChIKey | HUOFUOCSQCYFPW-UHFFFAOYSA-N | | CAS DataBase Reference | 139301-27-2(CAS DataBase Reference) |
| | 4-Trifluoromethoxyphenylboronic acid Usage And Synthesis |
| Chemical Properties | white to beige crystalline powder | | Uses | B-[4-(Trifluoromethoxy)phenyl]boronic Acid is a reagent used in the synthesis of orally bioavailable matrix metalloprotinase inhibitors. Also used in the preparation of chromen-4-one inhibitors used against DNA dependant protein kinases. | | Application | 4-Trifluoromethoxyphenylboronic acid can reactant involved in the synthesis of biologically active molecules including:
Lactate dehydrogenase inhibitors for use against cancer cell proliferation
Nitro-phenoxybenzoic acid derivatives for PAI-1 inhibition
PA-824 analogs for use as antituberculosis drugs
Modulators of survival motor neuron protein
Reactant involved in addition reactions and cross-coupling reactions including Suzuki-Miyaura cross-coupling |
| | 4-Trifluoromethoxyphenylboronic acid Preparation Products And Raw materials |
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