10-Hydroxycanthin-6-one

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Products Intro: Product Name:10-Hydroxycanthin-6-one
CAS:86293-41-6
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CAS:86293-41-6
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CAS:86293-41-6
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Products Intro: Product Name:10-Hydroxycanthin-6-one
CAS:86293-41-6
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10-Hydroxycanthin-6-one Basic information
Product Name:10-Hydroxycanthin-6-one
Synonyms:10-Hydroxycanthin-6-one;Aervine;Ervine;NSC 341583;6H-Indolo[3,2,1-de][1,5]naphthyridin-6-one,10-hydroxy-
CAS:86293-41-6
MF:C14H8N2O2
MW:236.23
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Mol File:86293-41-6.mol
10-Hydroxycanthin-6-one Structure
10-Hydroxycanthin-6-one Chemical Properties
Boiling point 410.1±45.0 °C(Predicted)
density 1.53±0.1 g/cm3(Predicted)
pka8.96±0.20(Predicted)
Safety Information
MSDS Information
10-Hydroxycanthin-6-one Usage And Synthesis
DescriptionThe empirical formula for this alkaloid should read C21H24N203 and the structure is that given above. This alkaloid has been fully described by Malikov and his colleagues. It forms colourless crystals with m.p. 222-3°C from MeOH and has the following specific rotations: [α]D- 57.3° (c 2.01, MeOH) and [α] D - 83.5° (c 0.3, pyridine). Among the crystalline salts and derivatives that have been prepared are the hydrochloride, m.p. 265-8°C; hydrobromide, m.p. 285-6°C; hydriodide, m.p. 255-8°C and the methiodide, m.p. 258-260°C.
DefinitionChEBI: An indole alkaloid that is canthin-6-one substituted by a hydroxy group at position 10. Isolated from Simaba multiflora, it exhibits antineoplastic activity.
ReferencesMalikov, Yadishev, Yunusov, Khim. Prir. Soedin., 2, 338 (1966)
10-Hydroxycanthin-6-one Preparation Products And Raw materials
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