- Halobetasol propionate
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- $0.00 / 1kg
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2024-04-02
- CAS:66852-54-8
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 20tons
- Halobetasol propionate
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- $0.00 / 25KG
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2023-05-20
- CAS:66852-54-8
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 50000KG/month
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| | Halobetasol propionate Basic information |
| Product Name: | Halobetasol propionate | | Synonyms: | ulobetasol propionate;HALOBETASOL PROPIONATE;BMY-30056;CGP-14458;Uiobetasol Propionate;Ultravate;21-chloro-6alpha,9-difluoro-11beta,17-dihydroxy-16beta-methylpregna-1,4-diene-3,20-dione 17-propionate;6 alpha-fluoroclobetasol 17-propionate | | CAS: | 66852-54-8 | | MF: | C25H31ClF2O5 | | MW: | 484.96 | | EINECS: | 686-247-0 | | Product Categories: | Inhibitors;Steroids | | Mol File: | 66852-54-8.mol |  |
| | Halobetasol propionate Chemical Properties |
| Melting point | 213-215°C | | Boiling point | 570.7±50.0 °C(Predicted) | | density | 1.31±0.1 g/cm3(Predicted) | | storage temp. | Refrigerator | | solubility | Dioxane (Sparingly), DMSO (Slightly), Methanol (Slightly) | | form | Solid | | pka | 12.55±0.70(Predicted) | | color | White to Off-White | | InChIKey | BDSYKGHYMJNPAB-QNGYMBKVNA-N | | SMILES | O([C@@]1([C@H](C[C@@]2([H])[C@]3([H])C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]12C)C)C(=O)CCl)C(=O)CC |&1:1,2,4,6,9,17,19,21,24,r| | | CAS DataBase Reference | 66852-54-8(CAS DataBase Reference) |
| | Halobetasol propionate Usage And Synthesis |
| Description | Halobetasol propionate is a new ultra-potent topical corticosteroid exhibiting both
antiinflammatory and antihyperplasia properties. The compound is recommended for
the treatment of moderate to severe corticosteroid-responsive dermatoses and appears
to be particularly effective in patients with plaque psoriasis. It inhibits dermatitis induced by ultraviolet light in guinea pigs (ED50 = 1.45 μg/animal) and by oxazolone in mice (ED50 = 0.8 μg/animal). Halobetasol propionate also has anti-inflammatory effects on croton oil-induced ear edema in rats (ED50s = 10 μg/ml and 0.5 μg/ear) and mice (ED50s = 1.2 and <0.32 μg/ear after 6 and 24 hours of treatment, respectively). Topical formulations containing halobetasol propionate have been used for inflammatory and pruritic dermatitis. | | Chemical Properties | White Solid | | Originator | Ciba-Geigy (Switzerland) | | Uses | Halobetasol propionate is a corticosteroid (cortisone-like medicine or steroid). As an anti-inflammatory drug, halobetasol topical is used to help relieve redness, itching, swelling, or other discomfort caused by certain skin conditions. It is also used to treat plaque psoriasis.This medicine is available only with doctor's prescription.
| | Definition | ChEBI: Ulobetasol propionate is a corticosteroid hormone. | | Brand name | Ultravate (Westwood-Squibb). |
| | Halobetasol propionate Preparation Products And Raw materials |
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