| Company Name: |
Hefei fuya biotechnology co. LTD Gold
|
| Tel: |
18096409024 |
| Email: |
sales02@foreversyn.com |
| Products Intro: |
Product Name:bafilomycin B1
CAS:88899-56-3
Package:25mg/;100mg/
|
- Bafilomycin B1
-
- $0.01 / 1KG
-
2020-05-13
- CAS:88899-56-3
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 50 tons
|
| | BAFILOMYCIN B1 Basic information |
| Product Name: | BAFILOMYCIN B1 | | Synonyms: | BAFILOMYCIN B1;BAFILOMYCIN B1 MONOHYDRATE FROM STREPTO- MYCES SPECIES;BafilomycinB1fromStreptomycesgriseus;bafilomycin b1from streptomyces sp.;hygrolidin,37-decarboxy-2-demethyl-37-(((2-hydroxy-5-oxo-1-cyclopenten-1-yl)am;ino)carbonyl)-2-methoxy-24-methyl-;37-De(carboxy)-2-demethyl-37-[[(2-hydroxy-5-oxo-1-cyclopenten-1-yl)amino]carbonyl]-2-methoxy-24-methylhygrolidin;2-Butenoic acid, 4-[(2-hydroxy-5-oxo-1-cyclopenten-1-yl)amino]-4-oxo-, (2R,4R,5S,6R)-tetrahydro-2-hydroxy-2-[(1S,2R,3S)-2-hydroxy-3-[(2R,3S,4E,6E,9S,10S,11R,12E,14Z)-10-hydroxy-3,15-dimethoxy-7,9,11,13-tetramethyl-16-oxooxacyclohexadeca-4,6,12,14-tetraen-2-yl]-1-methylbutyl]-5-methyl-6-(1-methylethy... | | CAS: | 88899-56-3 | | MF: | C44H65NO13 | | MW: | 815.99 | | EINECS: | | | Product Categories: | Antibiotic;MacrolidesMore...Close...;A - KAntibiotics;Antibacterial;Antibiotics A to;Antibiotics A-FAntibiotics;Antibiotics by Application;AntifungalAntibiotics;Antineoplastic and Immunosuppressive AntibioticsAntibiotics;Chemical Structure Class;Inhibits an EnzymeAntibiotics;Mechanism of Action;Spectrum of Activity | | Mol File: | 88899-56-3.mol |  |
| | BAFILOMYCIN B1 Chemical Properties |
| storage temp. | −20°C | | solubility | DMSO: Soluble; Methanol: Unstable | | form | powder or crystals | | color | faint yellow to yellow | | BRN | 4640118 | | Stability: | Hygroscopic |
| Hazard Codes | T+ | | Risk Statements | 26/27/28 | | Safety Statements | 36/37/39-45 | | RIDADR | UN 3462 6.1/PG 1 | | WGK Germany | 3 | | RTECS | NG8841000 | | F | 10-21 | | HazardClass | 3 | | HS Code | 2941900000 |
| | BAFILOMYCIN B1 Usage And Synthesis |
| Description | Bafilomycin B1 is a fungal metabolite that has been found in Streptomyces and has diverse biological activities. It inhibits the activity of rat liver lysosomal vacuolar H+-ATPase (V-ATPase) in a concentration-dependent manner. Bafilomycin B1 (10-1,000 nM) induces autophagosome accumulation in MCF-7 cells. It inhibits chloroquine-induced apoptosis in primary cerebellar granule neurons (CGNs) when used at a concentration of 1 nM. Bafilomycin B1 reduces viral genome copy numbers in the culture supernatant of Vero E6 cells infected with H1N1 influenza A. | | Uses | Bafilomycin B1 is a member of a potent family of macrocyclic lactones. Bafilomycin B1 shares the same mode of action and activity as its more accessible A1 analogue. Bafilomycin B1 is broadly active against bacteria, fungi, insects, nematodes and protozoans. Bafilomycin B1 has attracted interest as a potential agent for treating osteoporosis. |
| | BAFILOMYCIN B1 Preparation Products And Raw materials |
|