- Fmoc-L-Ser(tBu)-OH
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- $0.00/ kg
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2024-04-25
- CAS:71989-33-8
- Min. Order: 1kg
- Purity: 98%
- Supply Ability: 1T
- Fmoc-Ser(tbu)-OH
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- $0.00 / 25kg
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2023-07-22
- CAS:71989-33-8
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 2T/month
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| | FMOC-O-tert-Butyl-L-serine Basic information |
| | FMOC-O-tert-Butyl-L-serine Chemical Properties |
| Melting point | 130.5-135.5 °C(lit.) | | alpha | 25 º (c=1,EtOAc 24 ºC) | | Boiling point | 510.36°C (rough estimate) | | density | 1.2369 (rough estimate) | | refractive index | 24 ° (C=1, AcOEt) | | storage temp. | 2-8°C | | solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | | form | powder to crystal | | pka | 3.44±0.10(Predicted) | | color | White to Almost white | | optical activity | [α]20/D +25.5±1°, c = 1% in ethyl acetate | | BRN | 3632013 | | InChI | InChI=1S/C22H25NO5/c1-22(2,3)28-13-19(20(24)25)23-21(26)27-12-18-16-10-6-4-8-14(16)15-9-5-7-11-17(15)18/h4-11,18-19H,12-13H2,1-3H3,(H,23,26)(H,24,25)/t19-/m0/s1 | | InChIKey | REITVGIIZHFVGU-IBGZPJMESA-N | | SMILES | C(O)(=O)[C@H](COC(C)(C)C)NC(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)=O | | CAS DataBase Reference | 71989-33-8(CAS DataBase Reference) |
| | FMOC-O-tert-Butyl-L-serine Usage And Synthesis |
| Chemical Properties | white to light yellow crystal powde | | Uses | Fmoc-Ser(tBu)-OH is an N-terminal protected reagent used in the peptide synthesis. Some of the reported examples are:
- Total synthesis of an antibiotic, daptomycin, by cyclization via a chemoselective serine ligation.
- Preparation of MUC1, a T-cell helper peptide, using iterative pentafluorophenyl ester-mediated fragment condensations.
- Linear solid-phase peptide synthesis of ubiquitin and diubiquitin.
| | General Description | The product number for this product was previously 04-12-1033.
To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”. |
| | FMOC-O-tert-Butyl-L-serine Preparation Products And Raw materials |
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