- GC376
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- $30.00 / 1kg
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2023-09-08
- CAS:1416992-39-6
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 1000t/year
- GC376;GC-376 sodium
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- $1.00 / 1g
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2021-10-08
- CAS:1416992-39-6
- Min. Order: 1ASSAYS
- Purity: 98%+
- Supply Ability: 10kgs
- GC376 sodium
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- $6.60 / 1KG
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2019-12-31
- CAS:1416992-39-6
- Min. Order: 1KG
- Purity: 97%-99%
- Supply Ability: 1kg-1000kg
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| Product Name: | GC376 | | Synonyms: | GC376;GPC376;3 alpha, 7 alpha-dyhydroxy-6-ethidene- cholanic acid;Sodium (2S)-2-((S)-2-(((benzyloxy)carbonyl)amino)-4-methylpentanamido)-1-hydroxy-3-(2-oxopyrrolidin-3-yl)propane-1-sulfonate;(βS)-α-Hydroxy-β-[[(2S)-4-methyl-1-oxo-2-[[(phenylmethoxy)carbonyl]amino]pentyl]amino]-2-oxo-3-pyrrolidinepropanesulfonic acid sodium salt;376;GC376 sodium;GC376 (sodium salt) | | CAS: | 1416992-39-6 | | MF: | C21H32N3NaO8S | | MW: | 509.55 | | EINECS: | | | Product Categories: | | | Mol File: | 1416992-39-6.mol |  |
| | GC376 Chemical Properties |
| storage temp. | Inert atmosphere,Store in freezer, under -20°C | | solubility | DMF: 10 mg/ml,DMSO: 10 mg/ml,PBS (pH 7.2): 10 mg/ml | | form | A crystalline solid |
| | GC376 Usage And Synthesis |
| Description | GC376 is an inhibitor of the main protease Mpro (3CLpro) in coronaviruses as well as picornaviruses. This broad-spectrum antiviral compound has been used as investigational veterinary drug for treatment of feline infectious peritonitis virus (FIPV) infections. Recent studies also showed that GC376 inhibits the main protease Mpro (3CLpro) from SARS-CoV-2 with IC50 of 0.03 μM and EC50 of 3.37 μM. | | Uses | GC 376 sodium is a potential small molecule inhibitor which may be able to reduce the viral load of SARS-CoV-2 3CLpro. |
| | GC376 Preparation Products And Raw materials |
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