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| | BAY-1163877 Basic information |
| Product Name: | BAY-1163877 | | Synonyms: | BAY-1163877;2-Piperazinone, 4-[[4-amino-6-(methoxymethyl)-5-(7-methoxy-5-methylbenzo[b]thien-2-yl)pyrrolo[2,1-f][1,2,4]triazin-7-yl]methyl]-;Rogaratinib (BAY1163877);4-{[4-amino-6-(methoxymethyl)-5-(7-methoxy-5-methyl-1-benzothiophen-2-yl)pyrrolo[2,1-f]-[1,2,4]triazin-7-yl]methyl}piperazin-2-one;Rogaratinib;Rogaratinib,inhibit,BAY 1163877,Fibroblast growth factor receptor,BAY-1163877,FGFR,Inhibitor | | CAS: | 1443530-05-9 | | MF: | C23H26N6O3S | | MW: | 466.56 | | EINECS: | | | Product Categories: | | | Mol File: | 1443530-05-9.mol |  |
| | BAY-1163877 Chemical Properties |
| density | 1.48±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMSO:5.0(Max Conc. mg/mL);10.72(Max Conc. mM) | | pka | 15.49±0.20(Predicted) |
| | BAY-1163877 Usage And Synthesis |
| | BAY-1163877 Preparation Products And Raw materials |
| Raw materials | 6-(methoxymethyl)pyrrolo[2,1-f][1,2,4]triazin-4-amine-->ETHYL 4-AMINOPYRROLO[2,1-F][1,2,4]TRIAZINE-6-CARBOXYLATE-->Pyrrolo[2,1-f][1,2,4]triazine-6-methanol, 4-amino--->Benzenethiol, 2-methoxy-4-methyl--->7-Methoxy-5-Methylbenzo[b]thiophene-->(7-Methoxy-5-Methylbenzo[b]thiophen-2-yl)boronic acid-->2-Piperazinone-->2-methoxy-p-toluidine-->(2,2-diethoxyethyl)(2-methoxy-4-methylphenyl)sulfane-->2-METHOXY-4-METHYLBENZENESULFONYL CHLORIDE-->4-AMinopyrrolo[1,2-f][1,2,4]triazine-6-carbonitrile-->5-METHYL-2-NITROANISOLE-->Formaldehyde |
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