N-(Propargyl-PEG2)-N-Boc-PEG3-t-butyl ester

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Products Intro: Product Name:N-(Propargyl-PEG2)-N-Boc-PEG3-t-butyl ester
CAS:2093152-78-2
Purity:98.00% Package:100 mg;500 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
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Products Intro: Product Name:N-(Propargyl-PEG2)-N-Boc-PEG3-t-butyl ester
CAS:2093152-78-2
Purity:95%+ Package:1g;5g;10g;25g;50g;100g; Remarks:accept Custom Synthesis Services, support large packing
Company Name: Xian confluore Biological Technology Co., Ltd.
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Products Intro: Product Name:N-(Propargyl-PEG2)-N-Boc-PEG3-t-butyl ester
CAS:2093152-78-2
Purity:>95.00% Package:500mg
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Products Intro: Product Name:N-(Propargyl-PEG2)-N-Boc-PEG3-t-butyl ester
CAS:2093152-78-2
Purity:98% Package:$1051.9/100mg;$2041.9/250mg;$3301.9/500mg;Bulk package Remarks:98%
Company Name: Xi'an Confluore Biological Technology Co., Ltd.  
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Products Intro: Product Name:N-(Propargyl-PEG2)-N-Boc-PEG3-t-butyl ester
CAS:2093152-78-2
Purity:95% HPLC Package:10MG;25MG;50MG;100MG;1G;5G

N-(Propargyl-PEG2)-N-Boc-PEG3-t-butyl ester manufacturers

N-(Propargyl-PEG2)-N-Boc-PEG3-t-butyl ester Basic information
Product Name:N-(Propargyl-PEG2)-N-Boc-PEG3-t-butyl ester
Synonyms:N-(Propargyl-PEG2)-N-Boc-PEG3-t-butyl ester;5,8,11-Trioxa-2-azatetradecanedioic acid, 2-[2-[2-(2-propyn-1-yloxy)ethoxy]ethyl]-, 1,14-bis(1,1-dimethylethyl) ester
CAS:2093152-78-2
MF:C25H45NO9
MW:503.63
EINECS:
Product Categories:
Mol File:2093152-78-2.mol
N-(Propargyl-PEG2)-N-Boc-PEG3-t-butyl ester Structure
N-(Propargyl-PEG2)-N-Boc-PEG3-t-butyl ester Chemical Properties
Boiling point 546.2±50.0 °C(Predicted)
density 1.069±0.06 g/cm3(Predicted)
solubility Soluble in DMSO, DMF, DCM
pka-1.61±0.70(Predicted)
Safety Information
MSDS Information
N-(Propargyl-PEG2)-N-Boc-PEG3-t-butyl ester Usage And Synthesis
DescriptionN-(Propargyl-PEG2)-N-Boc-PEG3-t-butyl ester is a click chemistry branched linker. The propargyl group can react with azide-bearing compounds through Click Chemistry, the t-butyl protected carboxyl group can also be deprotected under mild acidic conditions.
UsesN-(Propargyl-PEG2)-N-Boc-PEG3-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. N-(Propargyl-PEG2)-N-Boc-PEG3-t-butyl ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
IC 50PEGs; Alkyl/ether
References[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
N-(Propargyl-PEG2)-N-Boc-PEG3-t-butyl ester Preparation Products And Raw materials
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