| Company Name: |
Guangzhou Isun Pharmaceutical Co., Ltd
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| Tel: |
020-39119399 18927568969 |
| Email: |
isunpharm@qq.com |
| Products Intro: |
Product Name:bpV (HOpic)
CAS:722494-26-0
Purity:98.0% Package:1G; 25G; 1KG; 25KG
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| | BPV(HOPIC) Basic information |
| Product Name: | BPV(HOPIC) | | Synonyms: | BPV(HOPIC);DIPOTASSIUM BISPEROXO(5-HYDROXYPYRIDINE-2-CARBOXYL)OXOVANADATE (V);Bisperoxovanadium(HOpic);K2[VO(O2)2C6H4NO3];bpV(HOpic) (potassium salt);bpV(HOpic) (potassium salt, technical grade);MAPK/ERK,Phosphatase and tensin homolog,Inhibitor,PTEN,MMAC1,inhibit,PI3K/AKT,BpV(HOpic),signalling | | CAS: | 722494-26-0 | | MF: | C6H4K2NO8V | | MW: | 347.24 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File |  |
| | BPV(HOPIC) Chemical Properties |
| storage temp. | -20°C | | solubility | H2O: soluble20mg/mL, clear | | form | powder | | color | faint yellow to dark yellow |
| Hazard Codes | Xi | | Risk Statements | 36/38 | | Safety Statements | 26 | | WGK Germany | 3 |
| | BPV(HOPIC) Usage And Synthesis |
| Uses | bpV(HOpic) has been used in pharmacological perturbation of cell migration related signaling pathway. | | Biochem/physiol Actions | bpV(OHpic) is a bisperoxovanadium inhibitor of protein phosphotyrosine phosphatases with selectivity for PTEN, phosphatase and tensin homolog, a tumour suppressor phosphatase involved in cell cycle regulation. IC50 values for bpV(HOpic) are 14 nM for PTEN compared to 4.9 μM for PTPβ and 25.3 μM for PTP-1β. bpV(HOpic) has been shown to enhance PI3K/Akt signaling that could prevent myocardium from ischemia-reperfusion injury. |
| | BPV(HOPIC) Preparation Products And Raw materials |
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