L-Lactide

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L-Lactide manufacturers

  • L-Lactide
  • L-Lactide pictures
  • $10.00 / 1kg
  • 2024-05-08
  • CAS:4511-42-6
  • Min. Order: 1kg
  • Purity: 99%
  • Supply Ability: 20ton
  • L-Lactide
  • L-Lactide pictures
  • $6.00 / 1KG
  • 2024-04-22
  • CAS:4511-42-6
  • Min. Order: 1KG
  • Purity: More than 99%
  • Supply Ability: 2000KG/MONTH
  • L-Lactide
  • L-Lactide pictures
  • $8.00 / 25kg
  • 2024-01-06
  • CAS:4511-42-6
  • Min. Order: 1kg
  • Purity: 99%
  • Supply Ability: 200000
L-Lactide Basic information
Product Name:L-Lactide
Synonyms:L-3,6-Dimethyl-1,4-dioxane-2,5-dione;1,4-Dioxane-2,5-dione, 3,6-dimethyl-, (3S,6S)-;3,6-dimethyl-1,4-dioxane-2,5-quinone;L-(-)-LACTIDE 98+%;3,6-Dimethyl-2,5-p-dioxanedione;L-(-)-Lactide ,99%;L-3,6-DiMethyl-p-dioxane-2,5-dione;L-(-)-Dilactide (3S,6S)-(-)-3,6-Dimethyl-1,4-dioxane-2,5-dione
CAS:4511-42-6
MF:C6H8O4
MW:144.13
EINECS:224-832-0
Product Categories:Chiral Building Blocks;Dioxanes;Dioxanes & Dioxolanes;Functional Materials;Glycidyl Compounds, etc. (Chiral);Lactones & Lactides (for High-Performance Polymer Research);Reagent for High-Performance Polymer Research;Synthetic Organic Chemistry;4511-42-6
Mol File:4511-42-6.mol
L-Lactide Structure
L-Lactide Chemical Properties
Melting point 92-94 °C(lit.)
Boiling point 255°C
density 1.186±0.06 g/cm3(Predicted)
vapor pressure 0.311Pa at 25℃
refractive index 1.4475
storage temp. 2-8°C
solubility Soluble in chloroform, and methanol. Slightly soluble in benzene.
form Solid
color White to Off-White
optical activity[α]20/D 285°, c = 1 in toluene
Water Solubility 16.7g/L at 20℃
Sensitive Moisture Sensitive
BRN 82124
Stability:Hygroscopic
InChIKeyJJTUDXZGHPGLLC-IMJSIDKUSA-N
LogP0.4 at 25℃
CAS DataBase Reference4511-42-6(CAS DataBase Reference)
EPA Substance Registry System1,4-Dioxane-2,5-dione, 3,6-dimethyl-, (3S,6S)- (4511-42-6)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38-36
Safety Statements 26-37/39
WGK Germany 3
TSCA Yes
HS Code 29322090
MSDS Information
ProviderLanguage
SigmaAldrich English
ALFA English
L-Lactide Usage And Synthesis
DescriptionL-lactide (3,6-dimethyl-1,4-dioxane-2,5-dione) is a cyclic lactone that is derived from lactic acid. It has the molecular formula C3H6O2 and is an essential building block for synthesizing polylactic acid (PLA) plastics, which are widely used in the manufacturing industry.
Chemical PropertiesWhite crystal
Uses(3S)-cis-3,6-Dimethyl-1,4-dioxane-2,5-dione may be used in the synthesis of optically active terpyridine containing poly(L-lactide)s, polydisperse lactic acid oligomers, bicyclic and tricyclic lactide derivatives.
ApplicationL-Lactide is a monomer used to produce polylactic acid (PLA), which is a biodegradable thermoplastic that has many uses in the pharmaceutical industry. Additionally, L-Lactide can be used to modify existing drug carriers or create new ones from scratch. As such, the pharmaceutical industry relies heavily on L-Lactide for its versatile applications.
Flammability and ExplosibilityNon flammable
Purification MethodsThis is the cyclic dilactone of lactic acid. The (±)-cis-racemate has been distilled with b 142o/8mm; the distillate which solidifies gives yellow needles on recrystallisation from EtOH with m 128o, from Et2O with m 129o, or CHCl3 with m 126o , 1720-1740 cm-1. It hydrolyses in cold max H2O. [Carothers et al. J Am Chem Soc 54 772 1932]. A trans-form (probably RS,SR) has been reported which crystallises from Et2O with m 42-43o [Hummel et al. Acta Cryst (Sect B) 38 1679 1982]. The R,R -(+)-lactide has b 150o/2mm and crystallises from Et2O with m 95o , or m 96.5 -97.5o (from CHCl3) or m 97.7o (from EtOAc) and [] D +297o (c 1.2, *C6H6). The S,S-(-)-lactide has b 150o/2.5mm and crystallises from EtOAc with m 98.7o, or m 95o (from CHCl3) or m 96.5-97.5o (from CCl4) and []D -297o (c 1.2, *C6H6). [Toniolo et al. J Org Chem 35 6 1970, Beilstein 19 H 154, 19 I 179, 19 II 176, 19 IV 1927, 19/5 V 10.]
L-Lactide Preparation Products And Raw materials
Preparation ProductsEthyl lactate-->Butyl lactate
Tag:L-Lactide(4511-42-6) Related Product Information
Dimethyl carbonate Cyclohexane ETHANE Dimethyl sulfoxide Hexane Dimethyl fumarate Dimethyl ether N,N-Dimethylformamide Cyclohexene oxide Methylcyclohexane 1,4-Dioxane L-Homoserine lactone hydrochloride POLY(D,L-LACTIDE-CO-GLYCOLIDE) LACTIDE(D,L-),DL-LACTIDE,LACTIDE 2-hydroxypropionicacid,isopropylester 1,4-Dioxane-2,5-dione (S)-(-)-2-ACETOXYPROPIONIC ACID ETHYL (S)-(-)-2-METHOXYPROPIONATE