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Pleuromulin

Pleuromulin Suppliers list
Company Name: Henan DaKen Chemical CO.,LTD.
Tel: +86-371-66670886
Email: info@dakenchem.com
Products Intro: Product Name:Pleuromulin
CAS:125-65-5
Purity:99% Package:100g,500g,1kg,5kg,10kg
Company Name: Henan Tianfu Chemical Co.,Ltd.
Tel: 0371-55170693
Email: info@tianfuchem.com
Products Intro: CAS:125-65-5
Purity:99% Package:500G;1KG;5KG;25KG
Company Name: career henan chemical co
Tel: +86-371-86658258
Email: sales@coreychem.com
Products Intro: Product Name:Pleuromulin
CAS:125-65-5
Purity:98% Package:1KG;1USD
Company Name: Hebei Guanlang Biotechnology Co., Ltd.
Tel:
Email: sales3@crovellbio.com
Products Intro: Product Name:Pleuromulin
CAS:125-65-5
Purity:99% Package:1KG;10USD
Company Name: Xiamen AmoyChem Co., Ltd
Tel: +86 592-605 1114
Email: sales@amoychem.com
Products Intro: Product Name:Pleuromulin
CAS:125-65-5
Purity:95%~97%

Lastest Price from Pleuromulin manufacturers

  • Pleuromulin
  • US $10.00 / KG
  • 2021-09-04
  • CAS:125-65-5
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: 10 mt
  • Pleuromutilin
  • US $15.00-10.00 / KG
  • 2021-07-13
  • CAS:125-65-5
  • Min. Order: 1KG
  • Purity: 99%+ HPLC
  • Supply Ability: Monthly supply of 1 ton
  • Pleuromutilin
  • US $15.00-10.00 / KG
  • 2021-07-10
  • CAS:125-65-5
  • Min. Order: 1KG
  • Purity: 99%+ HPLC
  • Supply Ability: Monthly supply of 1 ton
Pleuromulin Basic information
Product Name:Pleuromulin
Synonyms:PLEUROMULIN;PLEUROMUTILIN;a4014c;antibioticbc757;bc757;drosopholinb;glycolicacid,8-esterwithoctahydro-5,8-dihydroxy-4,6,9,10-tetramethyl-6-viny;l-3a,9-propano-3ah-cyclopentacycloocten-1(4h)-one
CAS:125-65-5
MF:C22H34O5
MW:378.5
EINECS:204-747-5
Product Categories:Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:125-65-5.mol
Pleuromulin Structure
Pleuromulin Chemical Properties
Melting point 170-1710C
alpha D24 +20° (c = 3 in abs ethanol)
Boiling point 482.8±45.0 °C(Predicted)
density 1.15±0.1 g/cm3(Predicted)
storage temp. -20°C Freezer
solubility DMSO: >10mg/mL (warmed)
form powder
pka12.91±0.10(Predicted)
color white to beige
optical activity[α]/D +30 to +40° (c=1; CH2Cl2)
InChIKeyYSBXUHAJXRCCET-BKUNHTPHSA-N
Safety Information
WGK Germany 3
RTECS MC5408000
ToxicityLD50 in mice: >60 mg/kg (Kavanagh, 1952)
Pleuromulin Usage And Synthesis
Chemical PropertiesPleuromulin is Crystalline Solid
UsesAntibiotic substance produced by the basidiomycetes Pleurotus mutilus
UsesPleuromutilin is a diterpene produced by several species of basidomycete, notably the genus Pleurotus, discovered in 1951. Pleuromutilin is a potent and highly selective antibiotic active against a range of Gram positive bacteria, with no cross resistance to existing antibiotic classes due to its unique mode of action. Pleuromutilin inhibits protein synthesis by binding to domain V of 23S rRNA and this has led to the development of many semi-synthetic analogues as new generation antibiotics, such as tiamulin and retapamulin.
Pleuromutilins such as tiamulin and valnemulin have been used for some time in veterinary medicine to treat swine infections. More recently a semisynthetic pleuromutilin, retapamulin, has been introduced as a topical treatment for Gram-positive infections in humans. Pleuromutilins inhibit the peptidyl transferase activity of the bacterial 50S ribosomal subunit by binding to the A site.
Pleuromulin Preparation Products And Raw materials
Tag:Pleuromulin(125-65-5) Related Product Information
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