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8-ethyl-5-oxo-2-[4-[[3-(trifluoromethyl)phenyl]carbamothioyl]piperazin-1-yl]pyrido[2,3-d]pyrimidine-6-carboxylic acid

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8-ethyl-5-oxo-2-[4-[[3-(trifluoromethyl)phenyl]carbamothioyl]piperazin-1-yl]pyrido[2,3-d]pyrimidine-6-carboxylic acid Suppliers list
Company Name: Nantong HI-FUTURE Biology Co., Ltd.
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Products Intro: Product Name:ML328
CAS:634175-34-1
Purity:98% HPLC Package:100mg，500mg，1g，5g，10g
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Products Intro: Product Name:ML328
CAS:634175-34-1
Package:1 mg；10 mg；100 mg；200 mg；25 mg；5 mg；50 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd
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Products Intro: Product Name:ML328
CAS:634175-34-1
Purity:98 Package:500mg；1g；5g；10g；25g Remarks:Provide customized services
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Products Intro: Product Name:CID-1517823
CAS:634175-34-1
Purity:>=98% Package:500Mg;1g;5g;25g;100g;500g;1kg;5kg
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Products Intro: Product Name:ML328
CAS:634175-34-1
Purity:98% Package:5mg;10mg;25mg
8-ethyl-5-oxo-2-[4-[[3-(trifluoromethyl)phenyl]carbamothioyl]piperazin-1-yl]pyrido[2,3-d]pyrimidine-6-carboxylic acid Basic information
Product Name:8-ethyl-5-oxo-2-[4-[[3-(trifluoromethyl)phenyl]carbamothioyl]piperazin-1-yl]pyrido[2,3-d]pyrimidine-6-carboxylic acid
Synonyms:8-ethyl-5-oxo-2-[4-[[3-(trifluoromethyl)phenyl]carbamothioyl]piperazin-1-yl]pyrido[2,3-d]pyrimidine-6-carboxylic acid;Pyrido[2,3-d]pyrimidine-6-carboxylic acid, 8-ethyl-5,8-dihydro-5-oxo-2-[4-[thioxo[[3-(trifluoromethyl)phenyl]amino]methyl]-1-piperazinyl]-;ML328;CID-1517823;ML328,ML-328
CAS:634175-34-1
MF:C22H21F3N6O3S
MW:506.5
EINECS:
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Mol File:634175-34-1.mol
8-ethyl-5-oxo-2-[4-[[3-(trifluoromethyl)phenyl]carbamothioyl]piperazin-1-yl]pyrido[2,3-d]pyrimidine-6-carboxylic acid Structure
8-ethyl-5-oxo-2-[4-[[3-(trifluoromethyl)phenyl]carbamothioyl]piperazin-1-yl]pyrido[2,3-d]pyrimidine-6-carboxylic acid Chemical Properties
storage temp. Store at -20°C
solubility DMSO: 25 mg/mL (49.36 mM);Ethanol: Insoluble
Water Solubility Water: Insoluble
Safety Information
MSDS Information
8-ethyl-5-oxo-2-[4-[[3-(trifluoromethyl)phenyl]carbamothioyl]piperazin-1-yl]pyrido[2,3-d]pyrimidine-6-carboxylic acid Usage And Synthesis
Biological ActivityCID-1517823 (ML328) is a potent and selective inhibitor of bacterial AddAB and RecBCD helicase-nucleases, with IC50s of 1.0 and 4.8 μM.
References[1] Bannister TD, et al. 2012 Dec 17 [updated 2013 Apr 5]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010-.
8-ethyl-5-oxo-2-[4-[[3-(trifluoromethyl)phenyl]carbamothioyl]piperazin-1-yl]pyrido[2,3-d]pyrimidine-6-carboxylic acid Preparation Products And Raw materials
Tag:8-ethyl-5-oxo-2-[4-[[3-(trifluoromethyl)phenyl]carbamothioyl]piperazin-1-yl]pyrido[2,3-d]pyrimidine-6-carboxylic acid(634175-34-1) Related Product Information
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