Camostat manufacturers
- Camostat free base
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- $1520.00 / 25mg
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2024-10-28
- CAS:59721-28-7
- Min. Order:
- Purity:
- Supply Ability: 10g
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| | Camostat Basic information |
| Product Name: | Camostat | | Synonyms: | CAMOSTAT;4-[[4-[(Aminoiminomethyl)amino]benzoyl]oxy]benzeneaxetic acid 2-(dimethylamino)-oxoethyl ester;Camostat (base and/or unspecified salts);2-(Dimethylamino)-2-oxoethyl 4-(4-guanidinobenzoyloxy)phenylacetate;Camostat Monomethanesulfonate;FOY-305：Foipan;N，N-Dimethylcarbamoylmethyl-p(p-guanidinobenzoyloxy)phenylacetate;4-[[4-[(Aminoiminomethyl)amino]benzoyl]oxy]benzeneacetic acid 2-(dimethylamino)-2-oxoethyl ester | | CAS: | 59721-28-7 | | MF: | C20H22N4O5 | | MW: | 398.41 | | EINECS: | | | Product Categories: | API | | Mol File: | 59721-28-7.mol |  |
| | Camostat Chemical Properties |
| Boiling point | 590.5±60.0 °C(Predicted) | | density | 1.28±0.1 g/cm3(Predicted) | | pka | 10.17±0.10(Predicted) |
| | Camostat Usage And Synthesis |
| Uses | Camostat is an orally active trypsin inhibitor. Camostat can reduce pancreatic fibrosis induced by repeated administration of superoxide dismutase inhibitors in rats, and decrease the proliferation and activation of pancreatic stellate cells (PSCs)[1]. | | Definition | ChEBI: Camostat is a benzoate ester resulting from the formal condensation of the carboxy group of 4-guanidinobenzoic acid with the hydroxy group of 2-(dimethylamino)-2-oxoethyl (4-hydroxyphenyl)acetate. It is a potent inhibitor of the human transmembrane protease serine 2 (TMPRSS2) and its mesylate salt is currently under investigation for its effectiveness in COVID-19 patients. It has a role as an anticoronaviral agent, a serine protease inhibitor, an antifibrinolytic drug, an anti-inflammatory agent, an antiviral agent, an antihypertensive agent and an antineoplastic agent. It is a tertiary carboxamide, a carboxylic ester, a diester, a member of guanidines and a benzoate ester. It is functionally related to a 4-guanidinobenzoic acid. It is a conjugate base of a camostat(1+). | | References | [1] Emori Y, et al. Camostat, an oral trypsin inhibitor, reduces pancreatic fibrosis induced by repeated administration of a superoxide dismutase inhibitor in rats. J Gastroenterol Hepatol. 2005 Jun;20(6):895-9. DOI:10.1111/j.1440-1746.2005.03826.x |
| | Camostat Preparation Products And Raw materials |
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