| Company Name: |
SYNRYN PHARMA PVT LTD
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| Tel: |
+91 9392615244 |
| Email: |
sales@synryn.com |
| Products Intro: |
Product Name:Trans -Abacavir
CAS:783292-37-5
Purity:96% Package:500 mg
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| | Abacavir Basic information |
| Product Name: | Abacavir | | Synonyms: | Abacavir Impurity 4(Abacavir EP Impurity D);(Abacavir EP Impurity D);(1R,?4R)?-?rel-4-?[2-Amino-?6-?(cyclopropylamino)?-?9H-?purin-?9-?yl]?-?2-?cyclopentene-?1-?methanol;[(1R,4R)-4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]cyclopent-2-enyl]methanol;2-Cyclopentene-1-methanol, 4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]-, (1R,4R)-rel-;Trans -Abacavir | | CAS: | 783292-37-5 | | MF: | C14H18N6O | | MW: | 286.33 | | EINECS: | | | Product Categories: | | | Mol File: | 783292-37-5.mol |  |
| | Abacavir Chemical Properties |
| Boiling point | 636.0±65.0 °C(Predicted) | | density | 1.70±0.1 g/cm3(Predicted) | | pka | 14.86±0.10(Predicted) |
| | Abacavir Usage And Synthesis |
| Uses | (1R,?4R)?-?rel-4-?[2-Amino-?6-?(cyclopropylamino)?-?9H-?purin-?9-?yl]?-?2-?cyclopentene-?1-?methanol (Abacavir EP Impurity D) is an impurity of Abacavir A105000). Abacavir is a carbocyclic 2''-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively. |
| | Abacavir Preparation Products And Raw materials |
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