Triazavirin
| 中文名称 | Triazavirin |
|---|---|
| 中文同义词 | 2-甲硫基-6-硝基-1,2,4-三唑并[5,1c][1,2,3]-三嗪-7-酮钠盐二水合物;7-(甲硫基)-3-硝基-[1,2,4]三唑并[5,1-C][1,2,4]三嗪环-4(6H)-酮钠盐二水化合物;瑞米拉韦;化合物TRIAZAVIRIN |
| 英文名称 | Triazavirin |
| 英文同义词 | Sodium 2-methylthio-6-nitro-1,2,4-triazol [5,1c][1,2,3]-triazin-7-one dihydrate;1,2,4]Triazolo[5,1-c][1,2,4]triazin-4(6H)-one, 7-(methylthio)-3-nitro-, sodium salt, hydrate;Triazavirin;Sodium 7-(methylthio)-3-nitro-4-oxo-4H-[1,2,4]triazolo[5,1-c][1,2,4]triazin-6-ide dihydrate;Triazavirin (Riamilovir);Triazavirin sodium hydrate (TZV, Riamilovir);Inhibitor,DNA,influenza,transmission,encephalitis,antiviral,RNA,Triazavirin,DNA/RNA Synthesis,Nucleoside Antimetabolite/Analog,Tick-born,Influenza Virus,nucleoside,replication,inhibit |
| CAS号 | 928659-17-0 |
| 分子式 | C5H7N6NaO4S |
| 分子量 | 270.2 |
| EINECS号 | 690-013-3 |
| 相关类别 | 芳香族;API |
| Mol文件 | 928659-17-0.mol |
| 结构式 |  |
Triazavirin 性质
| 储存条件 | under inert gas (nitrogen or Argon) at 2-8°C |
|---|---|
| 溶解度 | 二甲基亚砜：125 mg/mL（436.76 mM） |
| 形态 | 固体 |
Nucleoside analogue; Influenza virus
The efficacy of Triazavirin against the tick-borne encephalitis virus is estimated in the sensitive cell culture. In a concentration of 128 mcg/mL Triazavirin is shown active in inhibition of the tick-borne encephalitis virus reproduction (strain Sofiin ) by accumulation in the SKEV cell culture.
The therapeutic efficacy Triazavirin against experimental Forest-Spring encephalitis on albino mice is studied. The results shows that in high doses (200-400 mg/kg) Triazavirin moderately protects the infected animals. A significant increase of the animal lifespan in the test groups (from 4.1 to 4.8 days) and a statistically valid decrease of the virus accumulation in the target organ are observed.
安全信息
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2024/04/30 | HY-19743 | Triazavirin Triazavirin | 928659-17-0 | 5mg | 500元 |
| 2024/04/30 | HY-19743 | Triazavirin Triazavirin | 928659-17-0 | 10mg | 800元 |