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| | JTZ-951 hydrochloride Basic information |
| Product Name: | JTZ-951 hydrochloride | | Synonyms: | JTZ-951 hydrochloride;N-{[7-Hydroxy-5-(2-phenylethyl)[1,2,4]triazolo[1,5-a]pyridin-8-yl]carbonyl}glycine hydrochloride (1:1) | | CAS: | 1262131-60-1 | | MF: | C17H17ClN4O4 | | MW: | 376.8 | | EINECS: | | | Product Categories: | | | Mol File: | 1262131-60-1.mol |  |
| | JTZ-951 hydrochloride Chemical Properties |
| | JTZ-951 hydrochloride Usage And Synthesis |
| Description | Enarodustat, also known as JTZ-951, is a prolyl hydroxylase inhibitor. JTZ-951 (enarodustat) stabilizes HIF-α protein and induces erythropoiesis without effects on the function of vascular endothelial growth factor. Enarodustat increases endogenous erythropoietin levels in the treatment of anemia associated with chronic kidney disease (CKD). JTZ-951 induces erythropoiesis without affecting VEGF function. JTZ-951 may be a new oral candidate that increases and maintains hemoglobin concentrations in renal anemia patients. |
| | JTZ-951 hydrochloride Preparation Products And Raw materials |
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