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Linocaine hydrochloride

Linocaine hydrochloride Suppliers list
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Products Intro: Product Name:Lidocaine hydrochloride
CAS:6108-05-0
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Products Intro: Product Name:Lidocaine hydrochloride monohydrate
CAS:6108-05-0
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CAS:6108-05-0
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Products Intro: Product Name:Lidocaine hydrochloride
CAS:6108-05-0
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Products Intro: Product Name:Linocaine hydrochloride
CAS:6108-05-0
Purity:99% Package:1KG;40.00;USD Remarks:Medical grade

Linocaine hydrochloride manufacturers

  • Linocaine hydrochloride
  • Linocaine hydrochloride pictures
  • $5.00 / 1kg
  • 2024-03-28
  • CAS:6108-05-0
  • Min. Order: 1kg
  • Purity: 99.5
  • Supply Ability: 10 ton per month

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Linocaine hydrochloride Basic information
Product Name:Linocaine hydrochloride
Synonyms:Lignocaine monohydrate hydrochloride, Xylocaine monohydrate hydrochloride, 2-Diethylamino-N-(2,6-dimethylphenyl)acetamide monohydrate hydrochloride;2-Dimethylamino-N-(2,6-dimethylphenyl)acetamide hydrochloride;Lidocaine Hydrochloride BP98 USP24;Lignocaine hydrochloride monohydrate;Xylocaine hydrochloride monohydrate;Lidocaine Hydrochloride hydrate;Diethylamino-2,6-dimethylacetanilide hydrochloride;Lidocaine hydrochloride monohydrate,2-Diethylamino-N-(2,6-dimethylphenyl)acetamide hydrochloride monohydrate, Lignocaine hydrochloride monohydrate, Xylocaine hydrochloride monohydrate
CAS:6108-05-0
MF:C14H25ClN2O2
MW:288.82
EINECS:612-079-4
Product Categories:API;hydrochloride . hydrate;Other APIs;Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts;Sodium channel;Intermediate;6108-05-0
Mol File:6108-05-0.mol
Linocaine hydrochloride Structure
Linocaine hydrochloride Chemical Properties
Melting point 75-79℃
storage temp. 2-8°C
solubility H2O: soluble
form solid
color white
Water Solubility Soluble in water (50 mg/ml), chloroform, ethanol, and benzene. Insoluble in diethyl ether.
InChIInChI=1S/C14H22N2O.ClH.H2O/c1-5-16(6-2)10-13(17)15-14-11(3)8-7-9-12(14)4;;/h7-9H,5-6,10H2,1-4H3,(H,15,17);1H;1H2
InChIKeyYECIFGHRMFEPJK-UHFFFAOYSA-N
SMILESC1(C(C)=CC=CC=1C)NC(=O)CN(CC)CC.O.Cl
LogP2.359 (est)
CAS DataBase Reference6108-05-0(CAS DataBase Reference)
Safety Information
Hazard Codes Xn
Risk Statements 22
Safety Statements 36
RIDADR UN 2811 6.1/PG 3
WGK Germany 3
RTECS AN7700000
TSCA Yes
HazardClass 6.1
HS Code 2924296000
MSDS Information
ProviderLanguage
SigmaAldrich English
Linocaine hydrochloride Usage And Synthesis
Chemical PropertiesLinocaine hydrochloride is a white or almost white, crystalline powder with slightly bitter and numbing taste. Soluble in water, ethanol and organic solvents, insoluble in ether. The aqueous solution does not decompose under acid and alkali conditions, and it rarely deteriorates after repeated autoclaving.
UsesLinocaine hydrochloride is a fast voltage-gated sodium channel blocker that used in Local anesthesia and heart rhythm disorders. Its actions are more intense and its effects more prolonged than those of procaine but its duration of action is shorter than that of bupivacaine or prilocaine.
ApplicationAnesthetic (local); antiarrhythmic (class IB). Long-acting, membrane stabilizing agent against ventricular arrhythmia. Originally developed as a local anesthetic.
DefinitionChEBI: Linocaine hydrochloride is the monohydrate form of lidocaine hydrochloride. It is a local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of Procaine but its duration of action is shorter than that of bupivacaine or prilocaine.
Brand nameAlpha caine Hydrochloride (Carlisle); Anestacon (Polymedica); Laryng-O-Jet (International Medication); Lidocaton (Phar maton); Lidopen (Meridian); Xylocaine (Abraxis); Xylo caine (AstraZeneca); Xylocaine (Dentsply).
Contact allergensLinocaine hydrochloride is an anesthetic of the amide group, like articaine or bupivacaine. Immediate-type IgE-dependent reactions are rare, and delayed-type contact dermatitis is exceptional. Cross-reactivity between the different amide anesthetics is not systematic.
Mode of actionLidocaine Hydrochloride is the hydrochloride salt form of lidocaine, an aminoethylamide and a prototypical member of the amide class anesthetics. Lidocaine interacts with voltage-gated Na+ channels in the nerve cell membrane and blocks the transient increase in permeability of excitable membranes to Na+. This prevents the generation and conduction of nerve impulses and produces a reversible loss of sensation. Lidocaine hydrochloride also exhibits class IB antiarrhythmic effects. The agent decreases the flow of sodium ions into myocardial tissue, especially on the Purkinje network, during phase 0 of the action potential, thereby decreasing depolarization, automaticity and excitability.
Linocaine hydrochloride Preparation Products And Raw materials
Tag:Linocaine hydrochloride(6108-05-0) Related Product Information
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