ELEUTHEROSIDE B1(RG) manufacturers
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| | ELEUTHEROSIDE B1(RG) Basic information |
| Product Name: | ELEUTHEROSIDE B1(RG) | | Synonyms: | ELEUTHEROSIDE B1(RG);2H-1-Benzopyran-2-one,7-(a-D-glucopyranosyloxy)-6,8-dimethoxy-;2H-1-Benzopyran-2-one, 7-(α-D-glucopyranosyloxy)-6,8-dimethoxy-;6,8-Dimethoxy-7-(((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-2H-chromen-2-one;Eleutheroside B 1,Influenza Virus,anti-inflammatory,virus,host,Eleutheroside B1,anti-influenza,Eleutheroside B-1,Inhibitor,genes,biosynthesis,inhibit | | CAS: | 16845-16-2 | | MF: | C17H20O10 | | MW: | 384.34 | | EINECS: | | | Product Categories: | | | Mol File: | 16845-16-2.mol |  |
| | ELEUTHEROSIDE B1(RG) Chemical Properties |
| Boiling point | 675.0±55.0 °C(Predicted) | | density | 1.524±0.06 g/cm3(Predicted) | | storage temp. | 4°C, away from moisture and light | | pka | 12.65±0.70(Predicted) |
| | ELEUTHEROSIDE B1(RG) Usage And Synthesis |
| Chemical Properties | White crystalline powder, soluble in chloroform, derived from the dried rhizome of Acanthopanax senticosus. | | Biological Activity | Eleutheroside B1, a coumarin compound, has broad-spectrum anti-human influenza virus (influenza virus) activity with IC50 values of 64-125μg/ml. It mediates its anti-influenza activity through POLR2A and N-glycosylation. Eleutheroside B1 inhibits mRNA expression of multiple chemokine genes and influenza virus nucleoprotein (NP) gene with low cytotoxicity. Has antiviral and anti-inflammatory activity. | | in vitro | Eeutheroside B1 (100 μg/ml; 24 hours) influences mRNA expression of host genes and virus genes in A549 cells. RT-PCR | Cell Line: | Virus-infected A549 cells | | Concentration: | 100 μg/ml | | Incubation Time: | 24 hours | | Result: | The expression of host genes (MAN2A2, POLR2A) and virus genes (PA, PB1, PB2, HA) were decreased. | |
| | ELEUTHEROSIDE B1(RG) Preparation Products And Raw materials |
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