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| | 2-Acetoxy-2-methylpropionyl bromide Basic information |
| | 2-Acetoxy-2-methylpropionyl bromide Chemical Properties |
| Boiling point | 75-77 °C12 mm Hg(lit.) | | density | 1.431 g/mL at 25 °C(lit.) | | refractive index | n20/D 1.457 | | Fp | >230 °F | | storage temp. | 2-8°C | | solubility | soluble in Chloroform, Methanol | | form | liquid | | color | Clear, pale yellow | | Sensitive | Moisture Sensitive | | BRN | 2432585 | | CAS DataBase Reference | 40635-67-4(CAS DataBase Reference) |
| Hazard Codes | C | | Risk Statements | 14-34-37 | | Safety Statements | 26-36/37/39-45 | | RIDADR | UN 3265 8/PG 2 | | WGK Germany | 3 | | F | 10-19 | | HazardClass | 8 | | PackingGroup | II | | HS Code | 29181980 |
| | 2-Acetoxy-2-methylpropionyl bromide Usage And Synthesis |
| Chemical Properties | light yellow clear liquid | | Uses | 1-Bromocarbonyl-1-methylethyl acetate (α-Acetoxyisobutyryl bromide) may be used:
- in the chemoenzymatic synthesis of (1R,2S)-1,2-epoxy-1,2-dihydroacridine (acridine 1,2-oxide)
- in the synthesis of protected 3′-deoxyadenosine and 3′-deoxyguanosine
- as reagent for deoxygenation of vicinal diols, as well as in the preparation of 2′,3′-dideoxycytidine and other dideoxy and deoxynucleosides from the corresponding ribo series.
| | General Description | 1-Bromocarbonyl-1-methylethyl acetate (α-Acetoxyisobutyryl bromide) participates in the conversion of adenosine to trans-3′(2′)-bromo-2′(3′)-acetates, via glycosyl cleavage. |
| | 2-Acetoxy-2-methylpropionyl bromide Preparation Products And Raw materials |
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