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Tianjin Kailiqi Biotechnology Co., Ltd.
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klq@cw-bio.com |
| Products Intro: |
Product Name:(S-1 METHANANDAMIDE)
CAS:157182-50-8
Purity:大于98% Package:1g,5g,10g,25g根据客户需要分装 Remarks:Not For Human Use, Lab Use Only.
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| Company Name: |
TargetMol Chemicals Inc.
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4008200310 |
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marketing@tsbiochem.com |
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Product Name:S-1 Methanandamide
CAS:157182-50-8
Purity:98% Package:100 mg；25 mg；50 mg
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| Company Name: |
ApexBio Technology
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+ 1-832-696-8203 |
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sales@apexbt.com |
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Product Name:S-1 Methanandamide
CAS:157182-50-8
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| Company Name: |
Cayman Chemical Company
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| Tel: |
(800) 364-9897 |
| Email: |
cayman@caymanchem.com |
| Products Intro: |
Product Name:S-1 Methanandamide
CAS:157182-50-8
Package:>98% Remarks:90072
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| | S-1 METHANANDAMIDE Basic information |
| Product Name: | S-1 METHANANDAMIDE | | Synonyms: | N-(2-HYDROXY-1S-METHYLETHYL)-5Z,8Z,11Z,14Z-EICOSATETRAENAMIDE;S-1 METHANANDAMIDE;S(-)-METHANANDAMIDE;(S)-(-)-ARACHIDONOYL-1'-HYDROXY-2'-PROPYLAMIDE;S(-)-ARACHIDONYL-1'-HYDROXY-2'-PROPYLAMIDE;S-1 Methanandamide Exclusive;5,8,11,14-Eicosatetraenamide, N-[(1S)-2-hydroxy-1-methylethyl]-, (5Z,8Z,11Z,14Z)-;(5Z,8Z,11Z,14Z)-N-[(2S)-1-hydroxypropan-2-yl]icosa-5,8,11,14-tetraenamide | | CAS: | 157182-50-8 | | MF: | C23H39NO2 | | MW: | 361.56 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File |  |
| | S-1 METHANANDAMIDE Chemical Properties |
| Boiling point | 529.0±50.0 °C(Predicted) | | density | 0.935±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | Soluble in DMSO;dimethyl formamide;acetonitril | | form | solution in ethanol. | | pka | 14.51±0.10(Predicted) |
| | S-1 METHANANDAMIDE Usage And Synthesis |
| Definition | ChEBI: S-1 methanandamide is a carboximidic acid. | | Biological Activity | s-1 methanandamide is a cb1 receptor ligand.the cannabinoid receptor type 1 (cb1), is a g protein-coupled cannabinoid receptor located mainly in the central and peripheral nervous system. cb1 is also expressed in several cells relating to metabolism, such as muscle cells, fat cells, liver cells, and the digestive tract. the cb1 receptor has been involved in the maintenance of homeostasis in health and disease, preventing the development of excessive neuronal activity, reducing pain and other inflammatory symptoms. enhanced receptor expression has been identified in human hepatocellular carcinoma tumor samples and human prostate cancer cells [2].s-1 methanandamide was a less potent than the c-1 (r) methyl isomer when binding with cb1 receptor. s-1 methanandamide inhibited electrically evoked contractions in isolated mouse vasa deferentia with an ic50 value of 230 nm. the binding affinity of s-1 methanandamide for cb1 receptors was less than that of aea, with a ki of 175 nm for the displacement of radiolabeled cp 55,940 [1]. | | references | [1] abadji v, lin s, taha g, et al. (r)-methanandamide: a chiral novel anandamide possessing higher potency and metabolic stability[j]. journal of medicinal chemistry, 1994, 37(12): 1889-1893.
[2] howlett a c. cannabinoid receptor signaling[m]//cannabinoids. springer berlin heidelberg, 2005: 53-79. |
| | S-1 METHANANDAMIDE Preparation Products And Raw materials |
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