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| | 4,5-DIMETHOXY-2-NITROBENZYL BROMIDE Basic information |
| Product Name: | 4,5-DIMETHOXY-2-NITROBENZYL BROMIDE | | Synonyms: | 4,5-DIMETHOXY-2-NITROBENZYL BROMIDE;4,5-Dimethoxy-2-nitrobenzyl bromide 95%;1-(bromomethyl)-2-nitro-4,5-dimethoxybenzene;4,5-dimenoxy-2-nitrobenzyl bromide;3,4-Dimethoxy-6-nitrobenzyl bromide;4,5-Dimethoxy-2-nitro-1-bromomethylbenzene;-4,5-dimethoxy-2-nitrobenzene;JR-13611, 1-(Bromomethyl)-4,5-dimethoxy-2-nitrobenzene, 97% | | CAS: | 53413-67-5 | | MF: | C9H10BrNO4 | | MW: | 276.08 | | EINECS: | | | Product Categories: | | | Mol File: | 53413-67-5.mol |  |
| | 4,5-DIMETHOXY-2-NITROBENZYL BROMIDE Chemical Properties |
| Melting point | 131-133 °C (lit.) | | Boiling point | 372.3±37.0 °C(Predicted) | | density | 1.544 | | storage temp. | under inert gas (nitrogen or Argon) at 2-8°C | | form | Crystalline Powder or Needles | | color | Yellow to brown | | Sensitive | Lachrymatory |
| Hazard Codes | C | | Risk Statements | 34 | | Safety Statements | 22-26-27-36/37/39-45 | | RIDADR | UN 3261 8/PG 2 | | WGK Germany | 3 | | HazardClass | 8 | | PackingGroup | III | | HS Code | 29093090 |
| | 4,5-DIMETHOXY-2-NITROBENZYL BROMIDE Usage And Synthesis |
| Uses | 1-(Bromomethyl)-4,5-dimethoxy-2-nitrobenzene is a useful research chemical. | | Uses | 4,5-Dimethoxy-2-nitrobenzyl bromide (DMNB bromide, 6-nitroveratryl bromide) is suitable reagent used in the synthesis of N-(4,5-dimethoxy-2-nitrobenzyl)vanillylamine which forms caged vanilloid. It may be used in the synthesis of the following:
- 4-(4′,5′-dimethoxy-2-nitrobenzyloxy)benzaldehyde, a DMNB-caged aldehyde
- N-[4-[(4,5-dimethoxy-2-nitrobenzyl)oxy]-3-methoxybenzyl]acetamide
- caged derivative of pyridostatin ([C]-PDS)
- photosensitive polyimide (PI-DMNB)
- caged β-ecdysone
- 4-tert-butyldimethylsilyloxy-1-(2-deoxy-3,5-di-O-toluoyl-β-D-ribofuranosyl)-2-(6-nitroveratrylthio)-1H-benzimidazole, an intermediate in synthesis of phosphoramidite bearing 4-hydroxy-2-mercaptobenzimidazole (SBNV) nucleobase
- alkylation of dihydrofluorescein
- 4-(4′,5′-Dimethoxy-2′-nitrobenzyloxy)benzaldehyde
| | General Description | 4,5-Dimethoxy-2-nitrobenzyl bromide (DMNBB, 1-(Bromomethyl)-4,5-dimethoxy-2-nitrobenzene) is a 4,5-dimethoxy-2-nitrobenzyl derivative. 4,5-Dimethoxy-2-nitrobenzyl (DMNB) group of DMNBB is used as a photolabile protecting group in caging technology to develop pro-drugs. Synthesis of 1-(bromomethyl)-4,5-dimethoxy-2-nitrobenzene by using 6-nitroveratraldehyde as starting reagent has been reported. |
| | 4,5-DIMETHOXY-2-NITROBENZYL BROMIDE Preparation Products And Raw materials |
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