Company Name: |
Bide Pharmatech Ltd.
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Tel: |
400-164-7117 13681763483 |
Email: |
product02@bidepharm.com |
Products Intro: |
Product Name:(R)-2-Acetamido-3-((2-amino-9-(4-chlorobenzyl)-6-oxo-6,9-dihydro-3H-purin-8-yl)thio)propanoic acid CAS:2241669-88-3 Purity:95% Package:10mg;25mg;50mg;100mg;250mg Remarks:BD01138729
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Company Name: |
Suzhou Chenrui Biotechnology Co. LTD
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Tel: |
17625585511 |
Email: |
1580084073@qq.com |
Products Intro: |
Product Name:E3 ligase Ligand 18 CAS:2241669-88-3 Purity:98% Package:1g;5g;10g
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| E3 ligase Ligand 18 Basic information |
Product Name: | E3 ligase Ligand 18 | Synonyms: | E3 ligase Ligand 18;L-Cysteine, N-acetyl-S-[2-amino-9-[(4-chlorophenyl)methyl]-6,9-dihydro-6-oxo-1H-purin-8-yl]-;(2R)-3-({2-amino-9-[(4-chlorophenyl)methyl]-6-oxo-6,9-dihydro-3H-purin-8-yl}sulfanyl)-2-acetamidopropanoic acid;(R)-2-Acetamido-3-((2-amino-9-(4-chlorobenzyl)-6-oxo-6,9-dihydro-3H-purin-8-yl)thio)propanoic acid | CAS: | 2241669-88-3 | MF: | C17H17ClN6O4S | MW: | 436.87 | EINECS: | | Product Categories: | | Mol File: | 2241669-88-3.mol |  |
| E3 ligase Ligand 18 Chemical Properties |
density | 1.68±0.1 g/cm3(Predicted) | pka | 3.17±0.10(Predicted) | form | Solid | color | White to off-white |
| E3 ligase Ligand 18 Usage And Synthesis |
Uses | E3 ligase Ligand 18 is a ligand for E3 ubiquitin ligase. E3 ligase Ligand 18 can be connected to the ligand for protein by a linker to form PROTACs. PROTACs are inducers of ubiquitination-mediated degradation of cancer-promoting proteins[1]. | IC 50 | Cereblon | References | [1] Heterocyclic compound. WO2018143403A1. |
| E3 ligase Ligand 18 Preparation Products And Raw materials |
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