| Company Name: |
TargetMol Chemicals Inc.
|
| Tel: |
4008200310 |
| Email: |
marketing@tsbiochem.com |
| Products Intro: |
Product Name:UCB-35440
CAS:299460-62-1
Package:100mg/RMB 21500;50mg/RMB 16800;25mg/RMB 12800
|
| Company Name: |
Suzhou Meishi Biotechnology Co., Ltd.
|
| Tel: |
1173954148q |
| Email: |
meishipharma@126.com |
| Products Intro: |
Product Name:299460-62-1
CAS:299460-62-1
Purity:99% HPLC Package:1G;5G;10G;100G;1KG;
|
Benzamide, 5-[4-[(aminocarbonyl)hydroxyamino]-1-butyn-1-yl]-2-[2-[4-[(R)-(4-chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]- manufacturers
- UCB-35440
-
- $3100.00 / 100mg
-
2025-10-27
- CAS:299460-62-1
- Min. Order:
- Purity:
- Supply Ability: 10g
|
| | Benzamide, 5-[4-[(aminocarbonyl)hydroxyamino]-1-butyn-1-yl]-2-[2-[4-[(R)-(4-chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]- Basic information |
| | Benzamide, 5-[4-[(aminocarbonyl)hydroxyamino]-1-butyn-1-yl]-2-[2-[4-[(R)-(4-chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]- Chemical Properties |
| Boiling point | 756.3±70.0 °C(Predicted) | | density | 1.37±0.1 g/cm3(Predicted) | | pka | 10.11±0.50(Predicted) |
| | Benzamide, 5-[4-[(aminocarbonyl)hydroxyamino]-1-butyn-1-yl]-2-[2-[4-[(R)-(4-chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]- Usage And Synthesis |
| Uses | UCB-35440 is an orally active histamine H1 receptor antagonist and 5-lipoxygenase inhibitor. UCB-35440 inhibits LTB4 formation in human whole blood and reduces polymorphonuclear cell infiltration in mouse models. UCB-35440 inhibits histamine-stimulated bronchoconstriction and reduces skin inflammation in guinea pigs. UCB-35440 can be used for research on asthma and skin inflammation[1][2]. | | References | [1] Giannaras A, et al. The effect of a novel, dual function histamine H1 receptor antagonist/5-lipoxygenase enzyme inhibitor on in vivo dermal inflammation and extravasation. Eur J Pharmacol. 2005 Jan 4;506(3):265-71. DOI:10.1016/j.ejphar.2004.11.003
[2] Oliver Werz, et al. Pharmacological intervention with 5-lipoxygenase: new insights and novel compounds. Expert Opin Ther Patents. 2005 May 10; 15(5):505-519. |
| | Benzamide, 5-[4-[(aminocarbonyl)hydroxyamino]-1-butyn-1-yl]-2-[2-[4-[(R)-(4-chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]- Preparation Products And Raw materials |
|