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Diphenyl ether

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Company Name: Dalian Richfortune Chemicals Co., Ltd
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Company Name: Henan DaKen Chemical CO.,LTD.
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Products Intro: Product Name:Diphenyl ether
CAS:101-84-8
Purity:99% Package:100g,500g,1KG,10KG,100KG
Company Name: Henan Tianfu Chemical Co.,Ltd.
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Purity:99% Package:500G;1KG;5KG;25KG
Company Name: Mainchem Co., Ltd.
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Products Intro: Product Name:Diphenyl oxide
CAS:101-84-8
Company Name: Shanghai Zheyan Biotech Co., Ltd.
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Products Intro: Product Name:Diphenyl ether
CAS:101-84-8
Purity:AR Package:250ml

Lastest Price from Diphenyl ether manufacturers

  • Diphenyl ether
  • US $1.00 / kg
  • 2019-07-06
  • CAS:101-84-8
  • Min. Order: 1 g
  • Purity: 99%
  • Supply Ability: 100KG
Diphenyl ether Basic information
Product Name:Diphenyl ether
Synonyms:1,1’-oxybis(benzene);1,1’-oxybis-benzen;1,1’-oxybisbenzene;1,1’-oxybis-Benzene;1,1'-Oxybisbenzene;1,1-Oxybisbenzene;Benzene, 1,1'-oxybis-;Benzene, phenoxy-
CAS:101-84-8
MF:C12H10O
MW:170.21
EINECS:202-981-2
Product Categories:Pharmaceutical Intermediates;FINE Chemical & INTERMEDIATES;Organics;Biphenyl & Diphenyl ether;DIG-DY;Pyridines ,Halogenated Heterocycles;Bioactive Small Molecules;Building Blocks;C11 to C12;Cell Biology;Chemical Synthesis;Ethers;Organic Building Blocks;Oxygen Compounds;-;Aromatics, Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
Mol File:101-84-8.mol
Diphenyl ether Structure
Diphenyl ether Chemical Properties
Melting point 26 °C
Boiling point 259 °C(lit.)
density 1.073 g/mL at 25 °C(lit.)
vapor density >5.86 (25 °C, vs air)
vapor pressure <1 mm Hg ( 20 °C)
refractive index n20/D 1.579(lit.)
FEMA 3667 | DIPHENYL ETHER
Fp >230 °F
storage temp. 2-8°C
solubility alcohol: soluble(lit.)
Specific Gravity1.073
Relative polarity2.8
OdorWeak geranium.
explosive limit0.8-1.5%(V)
Water Solubility insoluble
FreezingPoint 27℃
Merck 14,7288
JECFA Number1255
BRN 1364620
Henry's Law Constant2.13 at 20 °C (approximate - calculated from water solubility and vapor pressure)
Exposure limitsNIOSH REL: TWA 1 ppm (7 mg/m3), IDLH 100 ppm; OSHA PEL: TWA 1 ppm; ACGIH TLV: TWA 0.1, STEL 2 ppm (adopted).
InChIKeyUSIUVYZYUHIAEV-UHFFFAOYSA-N
CAS DataBase Reference101-84-8(CAS DataBase Reference)
NIST Chemistry ReferenceDiphenyl ether(101-84-8)
EPA Substance Registry SystemBenzene, 1,1'-oxybis-(101-84-8)
Safety Information
Hazard Codes N,Xi,T
Risk Statements 51/53-36/37/38-39/23/24/25-23/24/25-36/38-36
Safety Statements 60-61-57-37/39-26-45-36/37
RIDADR UN 3077 9/PG 3
WGK Germany 2
RTECS KN8970000
Autoignition Temperature610 °C
TSCA Yes
HS Code 2909 30 10
HazardClass 9
PackingGroup III
Hazardous Substances Data101-84-8(Hazardous Substances Data)
ToxicityLD50 orally in Rabbit: 2450 mg/kg LD50 dermal Rabbit > 7940 mg/kg
MSDS Information
ProviderLanguage
ACROS English
SigmaAldrich English
ALFA English
Diphenyl ether Usage And Synthesis
DescriptionDiphenyl ether (diphenyl oxide) is a colorless liquid with a floral odor. It is a white, crystalline solid at temperatures below 80ºF (27ºC). It has low volatility, low solubility in water, and is stable at high temperatures. Avoid contact with oxidizing materials.
Liquid diphenyl oxide is used primarily in industry. It is used in the industrial setting as a heat transfer fluid. It is the major component of Dowtherm A® (an eutectic mixture of phenyl ether and biphenyl) and further as a chemical intermediate in the production of surface-active agents and hightemperature lubricants, and in perfumery due to its geranium-like odour (ACG99b). It is also used as a chemical intermediate in the manufacture of surfactants and fire retardants.
Diphenyl oxide (DPO) is manufactured using the direct phenol method.
synthesis of diphenyl ether
Chemical PropertiesDiphenyl oxide is a practically colorless crystalline solid with a strong geranium-like odor. clear pale yellowish liquid after melting. It is almost completely insoluble in water, but dissolves in most of the common organic solvents. Its high thermal stability at temperatures as high as 350 to 400°C. together with its noncorrosiveness and general chemical inertness make it eminently suitable as a component of high-boiling heat transfer media.
Chemical PropertiesDiphenyl Ether has not been observed in nature. It is a colorless liquid or a crystalline solid (mp 26.8°C) with an odor reminiscent of geranium leaves. Diphenyl ether is obtained as a by-product in the production of phenol by high-pressure hydrolysis of chlorobenzene. Because of its stability and low price, diphenyl ether is used in large quantities in soap perfumes.
Chemical PropertiesDiphenyl ether has a harsh, floral-green, metallic geranium-type odor.
Physical propertiesColorless solid or liquid with a geranium-like odor. An experimentally determined odor threshold concentration of 100 ppbv was reported by Leonardos et al. (1969).
OccurrenceReported found in muscat grapes, grilled beef, green tea, potato chips, buckwheat, Bourbon vanilla and lemon balm.
UsesPhenyl Ether is an Impurity of Propofol (P829750).
UsesDiphenyl ether is widely used as a heat transfer agent and a dye carrier. It can be used alone or as a mixture with other materials. Because of its reactivity, It can also be used as a raw material or chemical intermediate to produce commercial products. Diphenyl ether is used in the production of:
  1. Diphenyl ether is employed as a processing aid in the production of polyesters. It acts as a chemical intermediate in the production of surface active agents and high temperature lubricants, fire retardants like polybrominated diphenyl ethers (PBDEs) and fragrance for detergents.
  2. Heat transfer media – like DOWTHERMTM fluids used for heating industrial processes
  3. Alkylated diphenyl oxides – used to make surfactants, greases and lubricants
  4. Halogenated diphenyl oxides – used in insecticides, wood preservatives, and flame retardants for appliance casings in consumer electronic products
  5. High temperature solvents
  6. Coatings
  7. Textile dye labeling
  8. Plastics – like ethylene-propylene-diene monomer (EPDM) rubber that is used for membrane roofing materials
  9. Diphenyl ether plays a vital role in the Ferrario reaction to produce phenoxathiin, which finds application in polyamide and polyimide production. Involving similar reactions, diphenyl ether is a significant side product in the high-pressure hydrolysis of chlorobenzene in the production of phenol.
  10. Diphenyl ether is found in alcoholic beverages. Diphenyl ether is present in muscat grapes, green tea, vanilla, lemon balm, buckwheat, potato chips and grilled beef. Diphenyl ether is a flavouring ingredient.
DefinitionChEBI: An aromatic ether in which the oxygen is attached to two phenyl substituents. It has been found in muscat grapes and vanilla.
PreparationBy heating potassium phenolate with bromobenzene or with chlorobenzene at elevated temperatures.
Aroma threshold valuesAroma characteristics at 1.0%: grassy, musty, powdery, dry, terpy, ocimenelike, aromatic and hoplike with green juniper berry nuances.
Taste threshold valuesTaste characteristics at 10 ppm: dry chemical, floral rosey with carrot, tropical and hoplike terpy notes and a green vegetative and woody nuance.
General DescriptionColorless liquid with a mild pleasant odor. May float or sink in water. Freezing point is 81°F.
Air & Water ReactionsInsoluble in water.
Reactivity ProfileDiphenyl oxide can react with oxidizing materials. . A vigorous reaction occurred between the ether and chlorosulfuric acid.
Health HazardInhalation may cause nausea because of disagreeable odor. Contact of liquid with eyes causes mild irritation. Prolonged exposure of skin to liquid causes reddening and irritation. Ingestion produces nausea.
Fire HazardDiphenyl oxide is combustible.
Chemical ReactivityReactivity with Water No reaction; Reactivity with Common Materials: No reaction; Stability During Transport: Stable; Neutralizing Agents for Acids and Caustics: Not pertinent; Polymerization: Not pertinent; Inhibitor of Polymerization: Not pertinent.
Safety ProfileModerately toxic by ingestion. Prolonged exposure damages liver, spleen, kidneys, and thyroid, and upsets gastrointestinal tract. A skin and eye irritant. Combustible when exposed to heat or flame; can react with oxidizing materials. For explosion hazard, see ETHERS. To fight fire, use water, foam, CO2, dry chemical. When heated to decomposition it emits acrid smoke and irritating fumes
Purification MethodsCrystallise the ether from 90% EtOH. Melt it, wash it with 3M NaOH and water, dry it with CaCl2 and fractionally distil it under reduced pressure. Fractionally recrystallise it from its melt and store over P2O5. [Beilstein 6 IV 562.]
Diphenyl ether Preparation Products And Raw materials
Raw materialsSodium hydroxide-->Hydrochloric acid-->Potassium hydroxide -->Phenol-->Chlorobenzene-->Cupric sulfate-->Copper-->potassium phenolate
Preparation Products4-IODOQUINOLINE-->Decabromodiphenyl oxide-->7-TRIFLUOROMETHYL-4-QUINOLINETHIOL-->Triclosan-->6-bromoquinolin-4(3H)-one-->7-BROMO-3,4-DIHYDRO-4-OXOQUINOLINE-3-CARBOXYLIC ACID-->Piperazin-2-one-->ETHYL 4-CHLOROTHIENO[2,3-B]PYRIDINE-5-CARBOXYLATE-->9H-Carbazol-4-ol-->(OXYDI-2,1-PHENYLENE)BIS(DIPHENYLPHOSPHINE)-->7-(TRIFLUOROMETHYL)-4-QUINOLINOL-->4-HYDROXY-7-TRIFLUOROMETHYL-3-QUINOLINECARBOXYLIC ACID-->4-Hydroxy-2-methylquinoline-->5,7-BIS(TRIFLUOROMETHYL)-4-CHLOROQUINOLINE-->Nimesulide-->5,7-BIS(TRIFLUOROMETHYL)-4-HYDROXYQUINOLINE-->Pyriproxyfen-->3,4-DIHYDRO-8-HYDROXY-4-OXOQUINOLINE-3-CARBOXYLIC ACID-->Ethyl 7-bromo-3,4-dihydro-4-oxoquinoline-3-carboxylate ,97%-->5,7-BIS(TRIFLUOROMETHYL)-4-HYDROXYQUINOLINE-3-CARBOXYLIC ACID-->4-HYDROXY-5,7-BIS-TRIFLUOROMETHYL-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER-->4-HYDROXY-8-METHOXYQUINOLINE-3-CARBOXYLIC ACID-->4-Chloro-7-(trifluoromethyl)quinoline-->Tracid Brilliant Red B-->ETHYL 4-HYDROXY-7-(TRIFLUOROMETHYL)QUINOLINE-3-CARBOXYLATE-->ETHYL 4-HYDROXY-6-(TRIFLUOROMETHYL)QUINOLINE-3-CARBOXYLATE-->fluorocarbon sulfactant 6201-->3-METHYL-4-PYRIDINECARBOXYLIC ACID-->2-PHENOXYPHENYLBORONIC ACID-->4-HYDROXY-8-METHOXY-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER-->PHOSFOLAN-->A-METHYL-3-PHENOXYBENZENEACETALDEHYDE-->PHENOXATHIIN-->4-(4-chlorophenoxy-2‘-chlorophenyl-α-bromo ethanone)-->Disodium 4-dodecyl-2,4'-oxydibenzenesulfonate-->FENOPROFEN-->DICLOFOP-METHYL-->corrosion inhibitor PTX-4-->Pentabromodiphenyl ether-->TRIETHYL M-PHENOXYBENZYL AMMOUIUM CHLORIDE
Tag:Diphenyl ether(101-84-8) Related Product Information
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